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Article
Open AccessA Simulation Study of the Effect of Clinical Characteristics and Treatment Choice on Reliever Medication Use, Symptom Control and Exacerbation Risk in Moderate–Severe Asthma
The relationship between immediate symptom control, reliever medication use and exacerbation risk on treatment response and factors that modify it have not been assessed in an integrated manner. Here we apply ...
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Article
Open AccessExploring Clinical Remission in Moderate Asthma – Perspectives from Asia, the Middle East, and South America
Clinical remission is a relatively new concept in asthma but recent research initiatives suggest it could be an ambitious and achievable therapeutic target for patients with asthma.
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Article
Open AccessSexual and gender minority content in undergraduate medical education in the United States and Canada: current state and changes since 2011
To characterize current lesbian, gay, bisexual, transgender, queer, and intersex (LGBTQI +) health-related undergraduate medical education (UME) curricular content and associated changes since a 2011 study and...
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Article
Open AccessUnderstanding the Burden of Respiratory Syncytial Virus in Older Adults in Latin America: An Expert Perspective on Knowledge Gaps
Respiratory syncytial virus (RSV) is a significant global health concern and major cause of hospitalization, particularly among infants and older adults. The clinical impact of RSV is well characterized in inf...
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Article
Open AccessUnderstanding the Clinical Implications of Individual Patient Characteristics and Treatment Choice on the Risk of Exacerbation in Asthma Patients with Moderate–Severe Symptoms
The assessment of future risk has become an important feature in the management of patients with asthma. However, the contribution of patient-specific characteristics and treatment choices to the risk of exace...
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Article
Open AccessSABAs as Reliever Medications in Asthma Management: Evidence-Based Science
The role of as-needed inhaled short-acting β2-agonists (SABAs) in the management of asthma has become a subject of debate due to differing opinions in the professional community relating to the use of SABAs. In t...
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Article
Bevacizumab in real-life patients with recurrent glioblastoma: benefit or futility?
Angiogenesis plays a key role in glioblastoma, but most anti-angiogenic therapy trials have failed to change the poor outcome of this disease. Despite this, and because bevacizumab is known to alleviate sympto...
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Article
Open AccessSafety of SABA Monotherapy in Asthma Management: a Systematic Review and Meta-analysis
Short-acting β2-agonist (SABA) reliever overuse is common in asthma, despite availability of inhaled corticosteroid (ICS)-based maintenance therapies, and may be associated with increased risk of adverse events (...
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Article
Open AccessSunMap: A Solar Image Processing Software for Obtaining Synoptic Maps
A new open-source software, called SunMap, has been developed to obtain synoptic maps in an easy and quick way from multiple full-disc solar images. Our objective is to provide a free and straightforward appli...
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Article
Open AccessCorrection to: New Versus Old: The Impact of Changing Patterns of Inhaled Corticosteroid Prescribing and Dosing Regimens in Asthma Management
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Article
Open AccessNew Versus Old: The Impact of Changing Patterns of Inhaled Corticosteroid Prescribing and Dosing Regimens in Asthma Management
Inhaled corticosteroid (ICS)-containing therapies are the mainstay of pharmacological management of asthma. They can be administered alone or in combination with a long-acting bronchodilator, depending on asth...
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Article
Open AccessProlonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis
Patients with cancer are at higher risk of severe coronavirus infectious disease 2019 (COVID-19), but the mechanisms underlying virus–host interactions during cancer therapies remain elusive. When comparing na...
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Article
ROSI: A Robotic System for Harsh Outdoor Industrial Inspection - System Design and Applications
Belt Conveyors are essential for transporting dry bulk material in different industries. Such structures require permanent inspections, traditionally executed by human operators based on cognition. To improve ...
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Article
Improving flood forecasting through feature selection by a genetic algorithm – experiments based on real data from an Amazon rainforest river
This paper addresses the problem of feature selection aiming to improve a flood forecasting model. The proposed model is carried out through a case study that uses 18 different time series of thirty-five years...
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Article
Open AccessIntegrating deep learning CT-scan model, biological and clinical variables to predict severity of COVID-19 patients
The SARS-COV-2 pandemic has put pressure on intensive care units, so that identifying predictors of disease severity is a priority. We collect 58 clinical and biological variables, and chest CT scan data, from...
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Article
A Nationwide Study of Inpatient Admissions, Mortality, and Costs for Patients with Cirrhosis from 2005 to 2015 in the USA
Liver cirrhosis is a substantial health burden in the USA, but population-based data regarding the trend and medical expenditure are limited and outdated. We investigated the trends of inpatient admissions, co...
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Chapter and Conference Paper
Prostate Gland Segmentation in Histology Images via Residual and Multi-resolution U-NET
Prostate cancer is one of the most prevalent cancers worldwide. One of the key factors in reducing its mortality is based on early detection. The computer-aided diagnosis systems for this task are based on the...
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Chapter and Conference Paper
Analysis of Hand-Crafted and Automatic-Learned Features for Glaucoma Detection Through Raw Circumpapillary OCT Images
Taking into account that glaucoma is the leading cause of blindness worldwide, we propose in this paper three different learning methodologies for glaucoma detection in order to elucidate that traditional mach...
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Article
Routine multi detector computed tomography evaluation of tracheal impairment compared to laryngo-tracheal endoscopy in children with vascular ring
The aim of this study is to compare free-breathing routine multi detector computed tomography (MDCT) and laryngo-tracheal (LT) flexible endoscopy in the evaluation of tracheal impairment in children with vascu...
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Article
Open AccessHigher mortality and hospital charges in patients with cirrhosis and acute respiratory illness: a population-based study
Both cirrhosis and acute respiratory illness (ARI) carry substantial disease and financial burden. To compare hospitalized patients with cirrhosis with ARI to cirrhotic patients without ARI, a retrospective co...
