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Article
Antimicrobial effects of α-defensins from leukocytes of the hamadryas baboon Papio hamadryas
To understand the emergence and evolutionary selection of the efficient mechanisms of innate immunity it is necessary to accumulate knowledge about the structural and functional properties of antimicrobial pep...
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Article
Effects of defensin and lactoferrin on functional activity of endothelial cells in vitro
We studied the effects of antibacterial peptides and proteins (defensins and lactoferrins) on functional activity of endothelial cells in vitro: proliferative activity and adhesion of human endothelial ECV-304 ce...
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Article
α-Defensins from blood leukocytes of the monkey Papio hamadryas
Three antimicrobial peptides named PHD1-3 (Papio hamadryas defensin) have been isolated from hamadryas baboon blood leukocytes using preparative electrophoresis and reverse-phase HPLC. The primary structures of t...
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Article
Human placental myeloperoxidase in miscarriage
The activity of myeloperoxidase (MPO) was studied in chorionic and placental tissues of women with miscarriage. The MPO level reached the maximum during the first trimester both in normal pregnancy and in the ...
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Article
Formation of a complex of human plasma myeloperoxidase and opsonins
Human neutrophil myeloperoxidase adsorbs on immobilized fibronectin or IgG under conditions approaching the physiological ones. Immobilized myeloperoxidase binds liquid-phase plasma fibronectins and thermoaggr...
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Article
Functional activity of neutrophilic granulocytes in patients with relapsing herpes
Neutrophilic granulocytes exhibit different degrees of functional activity in patients with relapsing herpetic infection in various phases of the disease. A high level of myeloperoxidase is detected in the ser...