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  1. Article

    Open Access

    Testosterone positively regulates vagina NO-induced relaxation: an experimental study in rats

    Female sexual response involves a complex interplay between neurophysiological mechanisms and the nitric oxide (NO)-mediated relaxation of clitoris and vagina. The aim of this study was to evaluate sex steroid...

    I. Cellai, S. Filippi, P. Comeglio in Journal of Endocrinological Investigation (2022)

  2. Article

    Open Access

    Treatment potential of LPCN 1144 on liver health and metabolic regulation in a non-genomic, high fat diet induced NASH rabbit model

    Low free testosterone (T) level in men is independently associated with presence and severity of Non-Alcoholic Steatohepatitis (NASH). The histological and molecular effects of oral testosterone prodrug LPCN 1...

    P. Comeglio, E. Sarchielli, S. Filippi in Journal of Endocrinological Investigation (2021)

  3. No Access

    Chapter and Conference Paper

    A Software System for Predicting Trihalomethanes Species in Water Distribution Networks Using Online Networked Water Sensors

    Drinking water chlorination reduces the risk of pathogenic infection, but it may be harmful to human health because of trihalomethanes formation. At present, trihalomethanes concentrations are periodically mon...

    G. Fattoruso, A. Agresta, G. Guarnieri, M. Toscanesi in Sensors and Microsystems (2020)

  4. Article

    Open Access

    A regional assessment of cumulative impact map** on Mediterranean coralligenous outcrops

    In the last decade, the ‘Cumulative Pressure and Impact Assessment’ (CPIA) approach emerged as a tool to map expected impacts on marine ecosystems. However, CPIA assumes a linear response of ecosystems to incr...

    S. Bevilacqua, G. Guarnieri, G. Farella, A. Terlizzi, S. Fraschetti in Scientific Reports (2018)

  5. Article

    Open Access

    Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience

    In patients with asthma, particularly severe asthma, poor adherence to inhaled drugs negatively affects the achievement of disease control. A better adherence rate is expected in the case of injected drugs, su...

    M. Caminati, G. Senna, G. Stefanizzi, R. Bellamoli, S. Longhi in BMC Pulmonary Medicine (2016)

  6. Article

    Correction: Corrigendum: Coralligenous and maërl habitats: predictive modelling to identify their spatial distributions across the Mediterranean Sea

    Bioconstructions such as coralligenous outcrops and maërl beds are typical Mediterranean underwater seascapes. Fine-scale knowledge on the distribution of these sensitive habitats is crucial for their effectiv...

    C. S. Martin, M. Giannoulaki, F. De Leo, M. Scardi, M. Salomidi in Scientific Reports (2014)

  7. Article

    Open Access

    Coralligenous and maërl habitats: predictive modelling to identify their spatial distributions across the Mediterranean Sea

    Bioconstructions such as coralligenous outcrops and maërl beds are typical Mediterranean underwater seascapes. Fine-scale knowledge on the distribution of these sensitive habitats is crucial for their effectiv...

    C. S. Martin, M. Giannoulaki, F. De Leo, M. Scardi, M. Salomidi in Scientific Reports (2014)

  8. Article

    Fatty acids acutely enhance insulin-induced oxidative stress and cause insulin resistance by increasing mitochondrial reactive oxygen species (ROS) generation and nuclear factor-κB inhibitor (IκB)–nuclear factor-κB (NFκB) activation in rat muscle, in the absence of mitochondrial dysfunction

    Insulin effects reportedly involve reactive oxygen species (ROS) and oxidative stress in vitro, but skeletal muscle oxidative stress is an emerging negative regulator of insulin action following high-fat feedi...

    R. Barazzoni, M. Zanetti, G. Gortan Cappellari, A. Semolic, M. Boschelle in Diabetologia (2012)

  9. No Access

    Article

    Vertebroplasty as treatment of aggressive and symptomatic vertebral hemangiomas: up to 4 years of follow-up

    This study aimed to illustrate the validity of the treatment with vertebroplasty (VP) in patients with aggressive or symptomatic vertebral hemangioma (VH) with or without epidural extension.

    G. Guarnieri, G. Ambrosanio, P. Vassallo, M. G. Pezzullo, R. Galasso in Neuroradiology (2009)

  10. No Access

    Article

    Vertebroplasty and kyphoplasty: friends or foes?

    This paper aims to compare vertebroplasty and kyphoplasty by illustrating the two techniques, analysing the results and discussing the indications in relation to the type of fracture.

    M. Muto, V. Perrotta, G. Guarnieri, A. Lavanga, P. Vassallo in La radiologia medica (2008)

  11. No Access

    Article

    Low back pain and sciatica: treatment with intradiscal-intraforaminal O2-O3 injection. Our experience

    This paper describes discolysis by intradiscal, periganglionic and periradicular oxygen-ozone (O2-O3) injection, a minimally invasive percutaneous technique for the treatment of lumbar disk herniation.

    M. Muto, G. Ambrosanio, G. Guarnieri, E. Capobianco, G. Piccolo in La radiologia medica (2008)

  12. No Access

    Article

    Relation between the plasma levels of LDL-cholesterol and the expression of the early marker of inflammation long pentraxin PTX3 and the stress response gene p66(ShcA) in pacemaker-implanted patients

    Our goal was to set up a pilot study to explore the possible relation between the expression of p66(ShcA) and PTX3, two emerging regulators of stress response and inflammation processes, respectively, and the cir...

    A. Bosutti*, G. Grassi*, M. Zanetti, A. Aleksova in Clinical and Experimental Medicine (2007)

  13. No Access

    Chapter

    Pharmacological nutrition in ICU patients

    Depletion of body proteins is a major feature of critically ill patients [1, 2]. Despite enteral or parenteral feeding and treatment of the underlying disease, protein catabolism often persists and increases t...

    G. Guarnieri, G. Biolo in Metabolism and Artificial Nutrition in the Critically Ill (1999)

  14. No Access

    Chapter and Conference Paper

    Metabolism after Injury: The Effects of G.H.

    The metabolic response to severe trauma involves an increased loss of body proteins [1]. Specific sites of changes of protein and amino acid metabolism have been identified. In skeletal muscle, the rate of pro...

    G. Biolo, F. Iscra, G. Toigo, A. Gullo in Anaesthesia, Pain, Intensive Care and Emer… (1998)

  15. No Access

    Chapter

    Acute Effects of Carnitine Addition to the Dialysis Fluid During Hemodialysis in Patients with Chronic Renal Failure

    L-Carnitine (C) is required for intramitochondrial transport of FFA to the sites of beta-oxidation: in muscle the oxidation of long chain fatty acids is mostly C dependent. It is also accepted that C may shutt...

    G. Toigo, L. Crapesi, R. Situlin, G. Tamaro in Current Therapy in Nephrology (1989)

  16. No Access

    Article

    Dose-related effects of γ-amino β-hydroxy butyric acid (GABOB) infusion on growth hormone secretion in normal women

    The effect of γ-aminoβ-hydroxy butyric acid (GABOB) infusion on GH secretion has been investigated in 3 groups of 6 normal women. Different doses (100 mg/min, 20 mg/min, 3.5 mg/min) of GABOB diluted with norma...

    Dr. Gian B. Melis, A. M. Paoletti, V. Mais in Journal of Endocrinological Investigation (1982)