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    Novel Redox Active Tyrosine Mutations Enhance the Regeneration of Functional Oxyhemoglobin from Methemoglobin: Implications for Design of Blood Substitutes

    Heme mediated oxidative toxicity has been linked to adverse side effects in Hemoglobin Based Oxygen Carriers (HBOC), initiated by reactive ferryl (FeIV) iron and globin based free radical species. We recently sho...

    G. G. A. Silkstone, M. Simons, B. S. Rajagopal, T. Shaik… in Oxygen Transport to Tissue XL (2018)