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Open AccessApolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation
The lung is constantly exposed to the outside world and optimal adaptation of immune responses is crucial for efficient pathogen clearance. However, mechanisms that lead to lung-associated macrophages’ functio...
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Article
Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells
Breast cancer resistance to endocrine therapies such as tamoxifen and aromatase inhibitors is a significant clinical problem. Steroid receptor coactivator-1 (SRC-1), a coregulatory protein of the oestrogen rec...
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Article
Early-onset sepsis with Staphylococcus auricularis in an extremely low-birth weight infant – an uncommon pathogen
Coagulase-negative staphylococci (CoNS) are often dismissed as a contaminant of blood cultures and are rarely considered as an etiology of perinatally acquired infections. We describe a case of early-onset sep...
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Article
Chemistry and biology of maculalactone A from the marine cyanobacterium Kyrtuthrix maculans
Maculalactone A is the most abundant secondary metabolite in Kyrtuthrix maculans, a marine cyanobacterium found in the mid-high shore of moderately exposed to sheltered rocky shores in Hong Kong and South East As...
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Article
13C-2H correlation NMR spectroscopy studies of the in vivo transformations of natural products from Artemisia annua
13C-2H correlation NMR spectroscopy (13C-2H COSY) permits the identification of 13C and 2H nuclei which are connected to one another by a single chemical bond via the sizeable 1JCD coupling constant. The practic...
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Detection and Control of Fungi by Macrophages: The Role of Carbohydrates and Antifungal Agents
Macrophages play an important role in the innate immune response to fungal pathogens. They express receptors which recognise a variety of fungal molecular patterns, many of which are conserved cell wall carboh...
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Chapter
Phase Transitions in Polymer Blends and Block Copolymers Induced by Selective Dilation with Supercritical CO2
Supercritical fluids (SCFs) offer a number of advantages for the synthesis and processing of polymeric materials. Early work in the field focused on the high-pressure polymerization of ethylene or exploited th...
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Article
Isolation and characterisation of an aryl-β-D-glucoside uptake and utilisation system (abg) from the gram-positive ruminal Clostridium species C. longisporum
A phosphotransferase-dependent aryl-β-glucoside uptake and utilisation system (abg) was isolated from the ruminal Clostridium (“C. longisporum”). The system is composed of three genes, abgG, abgF and abgA, and a...
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Article
Modulation of swimming in Tritonia: excitatory and inhibitory effects of serotonin
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In the mollusc Tritonia escape swimming is produced by a network of central pattern generator (CPG) neurons. ...
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Tanacetum parthenium (L.) Schultz Bip. (Feverfew): In Vitro Culture and Prospects for the Production of Parthenolide
Tanacetum parthenium (L.) Schultz (Family Compositae) is a member of a genus of 14 species native to Europe and Asia; it has several synonyms: e.g., Matricaria parthenium L.; Chrysanthemum p...
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Article
Minimum Heart Rates of Marsupials
STUDIES of the nutrition and nitrogen metabolism of some macropod marsupials (kangaroos and wallabies) suggested that the level of energy metabolism of marsupials may be lower than that of eutherian mammals1.
