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  1. No Access

    Chapter and Conference Paper

    RIP2beta: Identifikation und Charakterisierung einer neuen alternativen Spleißvariante der Receptor Interacting Protein Kinase RIP2

    RIP2 is a member of the receptor interacting protein kinase (RIP) family. RIP2 activates NF-kappaB as well as the MAP-Kinases JNK, ERK1/2 and p38 MAPK, thereby playing an emergent role in the regulation of the...

    Dr. med A. Krieg, G. Le Negrate, W.T. Knoefel… in Chirurgisches Forum und DGAV Forum 2010 (2010)

  2. No Access

    Article

    IL-18-producing Salmonella inhibit tumor growth

    Previous studies have shown that intravenously applied bacteria can accumulate in tumors and lead to sporadic tumor regression. Recently, systemic administration of attenuated Salmonella typhimurium was demonstra...

    M Loeffler, G Le'Negrate, M Krajewska, J C Reed in Cancer Gene Therapy (2008)

  3. Article

    Downregulation of caspases and Fas ligand expression, and increased lifespan of neutrophils after transmigration across intestinal epithelium

    During inflammatory bowel diseases, commitment of extravased polymorphonuclear leucocytes (PMN) to apoptosis is required for the resolution of inflammation. To investigate the effect of transepithelial migrati...

    G Le'Negrate, P Rostagno, P Auberger, B Rossi, P Hofman in Cell Death & Differentiation (2003)

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