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  1. Article

    Open Access

    Placental extract suppresses lipid droplet accumulation by autophagy during the differentiation of adipose-derived mesenchymal stromal/stem cells into mature adipocytes

    Placental extract, which contains various bioactive compounds, has been used as traditional medicine. Many studies have demonstrated additional applications of placental extract and provided a scientific basis...

    Yusuke Ando, Eri Odawara, Hiroyasu Sakai, Fumiaki Sato, Junzo Kamei in BMC Research Notes (2023)

  2. No Access

    Article

    Ergot alkaloids in sclerotia collected in Japan: synthetic profiles and induction of apoptosis by Clavine-type compounds

    The genus Claviceps (Clavicipitaceae) is famous for producing ergot alkaloids (EAs) in sclerotia. EAs can cause ergotism, resulting in convulsions and necrosis when ingested, making these compounds a serious conc...

    Yuji Doi, Daigo Wakana, Satoshi Kitaoka, Fumiaki Sato in Journal of Natural Medicines (2023)

  3. No Access

    Article

    COL8A1 facilitates the growth of triple-negative breast cancer via FAK/Src activation

    Triple-negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes, and treatment options are limited because of the lack of signature molecules and heterogeneous properties of cancer. COL8...

    Fumiaki Sato, Atsunobu Sagara, Kaede Tajima in Breast Cancer Research and Treatment (2022)

  4. Article

    Open Access

    Backward and forward neck tilt affects perceptual bias when interpreting ambiguous figures

    The relationships between posture and perception have already been investigated in several studies. However, it is still unclear how perceptual bias and experiential contexts of human perception affect observe...

    Fumiaki Sato, Ryoya Shiomoto, Shigeki Nakauchi, Tetsuto Minami in Scientific Reports (2022)

  5. Article

    Open Access

    Impact of air temperature and drug concentration on liquid emission from elastomeric pumps

    Elastomeric pumps (EPs) are devices that allow quantitative and continuous drug administration without the need for electronic control, and they are used by being filled with anticancer agents. Although the pa...

    Tomoya Abe, Kazumasa Matsuzaka in Journal of Pharmaceutical Health Care and … (2021)

  6. Article

    Open Access

    Effect of different shielding conditions on the stability of Cisplatin

    Because cisplatin (CDDP) decreases upon light exposure, it is necessary to prevent such exposure during administration. However, the shielding conditions employed are not uniform. Therefore, in this study, we ...

    Tomoya Abe, Daigo Matsumoto in Journal of Pharmaceutical Health Care and … (2020)

  7. No Access

    Article

    Interference of Skin Scratching Attenuates Accumulation of Neutrophils in Murine Allergic Contact Dermatitis Model

    We recently reported that swelling resulting from 2,4,6-trinitrochlorobenzene (TNCB) challenge might be associated with recruitment of neutrophils. However, it is not known whether neutrophil recruitment is af...

    Hiroyasu Sakai, Taku Ishida, Ken Sato, Kazutaka Mandokoro, Saori Yabe in Inflammation (2019)

  8. Article

    Open Access

    Placental extract suppresses differentiation of 3T3-L1 preadipocytes to mature adipocytes via accelerated activation of p38 MAPK during the early phase of adipogenesis

    Adipogenesis, the process of preadipocyte differentiation to mature adipocytes accompanied by accumulation of intracytoplasmic lipid droplets, is regulated by various genetic and environmental factors, and clo...

    Yusuke Ando, Fumiaki Sato, Hazuki Fukunaga, Yusuke Iwasaki in Nutrition & Metabolism (2019)

  9. No Access

    Chapter and Conference Paper

    Securing of Clouds Based on Lightweight Secure Multi-party Computation

    To prevent leakage and misuse of data stored in the cloud, a secure computation method that can calculate encrypted data has been studied. Though early secure computations were not practical due to large compu...

    Kouta Takahashi, Fumiaki Sato in Complex, Intelligent, and Software Intensive Systems (2019)

  10. No Access

    Chapter and Conference Paper

    Deterrence System for Texting-While-Walking Focused on User Situation

    In recent years, users of smartphones are increasing explosively, and accidents and troubles due to texting-while-walking (TWW) are rapidly increasing along with this. Previous research on the TWW deterrence s...

    Megumi Fujiwara, Fumiaki Sato in Advances in Network-Based Information Systems (2019)

  11. No Access

    Article

    Real-time navigation system for sentinel lymph node biopsy in breast cancer patients using projection map** with indocyanine green fluorescence

    Inability to visualize indocyanine green fluorescence images in the surgical field limits the application of current near-infrared fluorescence imaging (NIR) systems for real-time navigation during sentinel ly...

    Masahiro Takada, Megumi Takeuchi, Eiji Suzuki, Fumiaki Sato in Breast Cancer (2018)

  12. No Access

    Chapter and Conference Paper

    Indoor Navigation System Based on Augmented Reality Markers

    Large-scale facilities have increased the demand for indoor navigation systems. In particular, indoor navigation using augmented reality (AR) markers is superior to other methods in terms of positioning accura...

    Fumiaki Sato in Innovative Mobile and Internet Services in Ubiquitous Computing (2018)

  13. No Access

    Chapter and Conference Paper

    Load Balancing in Wireless Mesh Networks Based on OpenFlow

    The wireless mesh network (WMN) is a state-of-the-art networking standard for the next generation of wireless networks. The construction of these networks is based on a network of wireless routers forwarding e...

    Shota Kubota, Fumiaki Sato in Advances in Network-Based Information Systems (2018)

  14. No Access

    Chapter and Conference Paper

    An Application Using a BLE Beacon Model Combined with Fully Autonomous Wheelchair Control

    This paper describes a novel technology for controlling a fully autonomous wheelchair, using a Bluetooth Low Energy (BLE) beacon. Our framework, in particular, enables the beacon substrate (Received Signal Str...

    Shugo Miyamoto, Takamasa Koshizen in Complex, Intelligent, and Software Intensi… (2018)

  15. No Access

    Article

    Effect of acute treadmill exercise on cisplatin-induced muscle atrophy in the mouse

    Cisplatin, a platinum-based anti-cancer drug, is one of the most effective broad-spectrum anti-cancer agents used against various cancers. It has been recently suggested that low skeletal muscle mass is predic...

    Hiroyasu Sakai, Minami Kimura, Yosuke Isa in Pflügers Archiv - European Journal of Phys… (2017)

  16. No Access

    Article

    Curcumin inhibits epigen and amphiregulin upregulated by 2,4,6-trinitrochlorobenzene associated with attenuation of skin swelling

    Contact dermatitis model involving repeated application of hapten is used as a tool to assess dermatitis, as characterized by thickening. Involvement of cell proliferation, elicited by repeated hapten-stimulat...

    Hiroyasu Sakai, Ken Sato, Fumiaki Sato, Yuki Kai in Inflammation Research (2017)

  17. Article

    Open Access

    Circulating cell-free DNA-based epigenetic assay can detect early breast cancer

    Circulating cell-free DNA (cfDNA) has recently been recognized as a resource for biomarkers of cancer progression, treatment response, and drug resistance. However, few have demonstrated the usefulness of cfDN...

    Natsue Uehiro, Fumiaki Sato, Fengling Pu, Sunao Tanaka in Breast Cancer Research (2016)

  18. No Access

    Article

    Genomic tumor evolution of breast cancer

    Owing to recent technical development of comprehensive genome-wide analysis such as next generation sequencing, deep biological insights of breast cancer have been revealed. Information of genomic mutations an...

    Fumiaki Sato, Shigehira Saji, Masakazu Toi in Breast Cancer (2016)

  19. Article

    Fuel, electricity, ER and HER2—a hybrid-car model of breast cancer

    Shigehira Saji, Fumiaki Sato, Naoto T. Ueno in Nature Reviews Clinical Oncology (2012)

  20. Article

    Open Access

    Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines

    Fascin induces membrane protrusions and cell motility. Fascin overexpression was associated with poor prognosis, and its downregulation reduces cell motility and invasiveness in esophageal squamous cell carcin...

    Cristian M Ortiz, Tetsuo Ito, Yosuke Hashimoto, Satoshi Nagayama in Diagnostic Pathology (2010)

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