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Article
Open AccessPlacental extract suppresses lipid droplet accumulation by autophagy during the differentiation of adipose-derived mesenchymal stromal/stem cells into mature adipocytes
Placental extract, which contains various bioactive compounds, has been used as traditional medicine. Many studies have demonstrated additional applications of placental extract and provided a scientific basis...
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Article
Ergot alkaloids in sclerotia collected in Japan: synthetic profiles and induction of apoptosis by Clavine-type compounds
The genus Claviceps (Clavicipitaceae) is famous for producing ergot alkaloids (EAs) in sclerotia. EAs can cause ergotism, resulting in convulsions and necrosis when ingested, making these compounds a serious conc...
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Article
COL8A1 facilitates the growth of triple-negative breast cancer via FAK/Src activation
Triple-negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes, and treatment options are limited because of the lack of signature molecules and heterogeneous properties of cancer. COL8...
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Article
Open AccessBackward and forward neck tilt affects perceptual bias when interpreting ambiguous figures
The relationships between posture and perception have already been investigated in several studies. However, it is still unclear how perceptual bias and experiential contexts of human perception affect observe...
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Article
Open AccessImpact of air temperature and drug concentration on liquid emission from elastomeric pumps
Elastomeric pumps (EPs) are devices that allow quantitative and continuous drug administration without the need for electronic control, and they are used by being filled with anticancer agents. Although the pa...
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Article
Open AccessEffect of different shielding conditions on the stability of Cisplatin
Because cisplatin (CDDP) decreases upon light exposure, it is necessary to prevent such exposure during administration. However, the shielding conditions employed are not uniform. Therefore, in this study, we ...
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Article
Interference of Skin Scratching Attenuates Accumulation of Neutrophils in Murine Allergic Contact Dermatitis Model
We recently reported that swelling resulting from 2,4,6-trinitrochlorobenzene (TNCB) challenge might be associated with recruitment of neutrophils. However, it is not known whether neutrophil recruitment is af...
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Article
Open AccessPlacental extract suppresses differentiation of 3T3-L1 preadipocytes to mature adipocytes via accelerated activation of p38 MAPK during the early phase of adipogenesis
Adipogenesis, the process of preadipocyte differentiation to mature adipocytes accompanied by accumulation of intracytoplasmic lipid droplets, is regulated by various genetic and environmental factors, and clo...
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Chapter and Conference Paper
Securing of Clouds Based on Lightweight Secure Multi-party Computation
To prevent leakage and misuse of data stored in the cloud, a secure computation method that can calculate encrypted data has been studied. Though early secure computations were not practical due to large compu...
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Chapter and Conference Paper
Deterrence System for Texting-While-Walking Focused on User Situation
In recent years, users of smartphones are increasing explosively, and accidents and troubles due to texting-while-walking (TWW) are rapidly increasing along with this. Previous research on the TWW deterrence s...
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Article
Real-time navigation system for sentinel lymph node biopsy in breast cancer patients using projection map** with indocyanine green fluorescence
Inability to visualize indocyanine green fluorescence images in the surgical field limits the application of current near-infrared fluorescence imaging (NIR) systems for real-time navigation during sentinel ly...
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Chapter and Conference Paper
Indoor Navigation System Based on Augmented Reality Markers
Large-scale facilities have increased the demand for indoor navigation systems. In particular, indoor navigation using augmented reality (AR) markers is superior to other methods in terms of positioning accura...
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Chapter and Conference Paper
Load Balancing in Wireless Mesh Networks Based on OpenFlow
The wireless mesh network (WMN) is a state-of-the-art networking standard for the next generation of wireless networks. The construction of these networks is based on a network of wireless routers forwarding e...
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Chapter and Conference Paper
An Application Using a BLE Beacon Model Combined with Fully Autonomous Wheelchair Control
This paper describes a novel technology for controlling a fully autonomous wheelchair, using a Bluetooth Low Energy (BLE) beacon. Our framework, in particular, enables the beacon substrate (Received Signal Str...
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Article
Effect of acute treadmill exercise on cisplatin-induced muscle atrophy in the mouse
Cisplatin, a platinum-based anti-cancer drug, is one of the most effective broad-spectrum anti-cancer agents used against various cancers. It has been recently suggested that low skeletal muscle mass is predic...
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Article
Curcumin inhibits epigen and amphiregulin upregulated by 2,4,6-trinitrochlorobenzene associated with attenuation of skin swelling
Contact dermatitis model involving repeated application of hapten is used as a tool to assess dermatitis, as characterized by thickening. Involvement of cell proliferation, elicited by repeated hapten-stimulat...
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Article
Open AccessCirculating cell-free DNA-based epigenetic assay can detect early breast cancer
Circulating cell-free DNA (cfDNA) has recently been recognized as a resource for biomarkers of cancer progression, treatment response, and drug resistance. However, few have demonstrated the usefulness of cfDN...
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Article
Genomic tumor evolution of breast cancer
Owing to recent technical development of comprehensive genome-wide analysis such as next generation sequencing, deep biological insights of breast cancer have been revealed. Information of genomic mutations an...
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Article
Fuel, electricity, ER and HER2—a hybrid-car model of breast cancer
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Article
Open AccessEffects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines
Fascin induces membrane protrusions and cell motility. Fascin overexpression was associated with poor prognosis, and its downregulation reduces cell motility and invasiveness in esophageal squamous cell carcin...