11 Result(s)

Article

Transcriptomic profiling of single circulating tumor cells provides insight into human metastatic gastric cancer

Transcriptome analysis of circulating tumor cells (CTCs), which migrate into blood vessels from primary tumor tissues, at the single-cell level offers critical insights into the biology of metastasis and contr...

Ryo Negishi, Hitomi Yamakawa, Takeru Kobayashi, Mayuko Horikawa… in Communications Biology (2022)

Article

Erratum to: Distribution angle control of a light-emitting diode downlight lens with high color uniformity using a scattering polymer

Keiichi Mochizuki, Kazumasa Oosumi, Fumiaki Koizumi, Yoshinori Shinohara… in Optical Review (2015)

Article

Pharmacodynamic change in plasma angiogenic proteins: a dose-escalation phase 1 study of the multi-kinase inhibitor lenvatinib

Lenvatinib (E7080), an oral multi-kinase inhibitor, has inhibitory action on tumor cell proliferation and tumor angiogenesis in preclinical models. We evaluated correlations between pharmacodynamic (PD) biomar...

Noriyuki Koyama, Kenichi Saito, Yuki Nishioka, Wataru Yusa, Noboru Yamamoto… in BMC Cancer (2014)

Article

A novel flow cytometry-based cell capture platform for the detection, capture and molecular characterization of rare tumor cells in blood

Personalized cancer treatment relies on the accurate detection of actionable genomic aberrations in tumor cells. Circulating tumor cells (CTCs) could provide an alternative genetic resource for diagnosis; howe...

Masaru Watanabe, Masakuni Serizawa, Takeshi Sawada… in Journal of Translational Medicine (2014)

Article

Epidermal growth factor receptor variant type III markedly accelerates angiogenesis and tumor growth via inducing c-myc mediated angiopoietin-like 4 expression in malignant glioma

Expression of the constitutively activated mutant EGFR variant III (EGFRvIII), the most common mutation in glioblastoma multiforme (GBMs), has been clinically correlated with tumor proliferation, invasion, and...

Yasufumi Katanasaka, Yasuo Kodera, Yuka Kitamura, Tatsuya Morimoto… in Molecular Cancer (2013)

Article

Circulating endothelial cells and other angiogenesis factors in pancreatic carcinoma patients receiving gemcitabine chemotherapy

Pancreatic carcinoma is a significant cause of cancer-related death in developed countries. As the level of circulating endothelial cells (CECs) is known to increase in response to various cancers, we investig...

Shunsuke Kondo, Hideki Ueno, Jun Hashimoto, Chigusa Morizane, Fumiaki Koizumi… in BMC Cancer (2012)

Article

Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3

Metastasis is a common event and the main cause of death in cancer patients. Lymphangiogenesis refers to the formation of new lymphatic vessels and is thought to be involved in the development of metastasis. S...

Yasuo Kodera, Yasufumi Katanasaka, Yuka Kitamura, Hitoshi Tsuda… in Breast Cancer Research (2011)