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Article
Open AccessAssociation of cognitive impairment and breast cancer survivorship on quality of life in younger breast cancer survivors
Younger breast cancer survivors (BCS) often report cognitive impairment and poor quality of life (QoL), which could be interrelated. The purpose of this study was to examine the association of cognitive impair...
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Article
Open AccessA PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study
Cardiovascular disease, diabetes, and kidney disease are among the leading causes of death and disability worldwide. However, knowledge of genetic determinants of those diseases in African Americans remains li...
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Article
Open AccessDetection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET
This study aimed to determine the pattern of [18F]flortaucipir uptake in individuals affected by Gerstmann-Sträussler-Scheinker disease (GSS) associated with the PRNP F198S mutation. The aims were to: 1) determin...
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Article
Open AccessImproving Recovery and Outcomes Every Day after the ICU (IMPROVE): study protocol for a randomized controlled trial
Delirium affects nearly 70% of older adults hospitalized in the intensive care unit (ICU), and many of those will be left with persistent cognitive impairment or dementia. There are no effective and scalable r...
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Article
Open AccessMobile critical care recovery program (m-CCRP) for acute respiratory failure survivors: study protocol for a randomized controlled trial
Patients admitted to intensive care units (ICU) with acute respiratory failure (ARF) face chronic complications that can impede return to normal daily function. A mobile, collaborative critical care model may ...
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Article
Open AccessCognitive function, body mass index and mortality in a rural elderly Chinese cohort
Previous studies have shown that poor cognition and low body mass index were associated with increased mortality. But few studies have investigated the association between cognition and mortality across the en...
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Article
Open AccessSelenium level and depressive symptoms in a rural elderly Chinese cohort
Selenium is considered a protective agent against free radicals through the maintenance of better enzyme activity. The few studies examining the relationship between selenium and depression have yielded incons...
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Article
Open AccessThe ACTIVE cognitive training trial and predicted medical expenditures
Health care expenditures for older adults are disproportionately high and increasing at both the individual and population levels. We evaluated the effects of the three cognitive training interventions (memory...