13 Result(s)
within
Frederick W Unverzagt
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Article
Multi-element Exposure and Cognitive Function in Rural Elderly Chinese
To investigate the relationship between selenium (Se) based multi-element combined exposure and cognitive function in rural elderly individuals, a cross-sectional study was conducted. The study involved 416 ol...
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Article
Blood Selenium and Serum Glutathione Peroxidase Levels Were Associated with Serum β-Amyloid in Older Adults
Studies have established the association between blood β-amyloid (Aβ) levels and Alzheimer’s disease, but population-based studies concerning the association between selenium (Se) and Aβ levels in blood sample...
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Open AccessAssociation of cognitive impairment and breast cancer survivorship on quality of life in younger breast cancer survivors
Younger breast cancer survivors (BCS) often report cognitive impairment and poor quality of life (QoL), which could be interrelated. The purpose of this study was to examine the association of cognitive impair...
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Open AccessA PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study
Cardiovascular disease, diabetes, and kidney disease are among the leading causes of death and disability worldwide. However, knowledge of genetic determinants of those diseases in African Americans remains li...
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Open AccessDetection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [18F]Flortaucipir PET
This study aimed to determine the pattern of [18F]flortaucipir uptake in individuals affected by Gerstmann-Sträussler-Scheinker disease (GSS) associated with the PRNP F198S mutation. The aims were to: 1) determin...
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Open AccessImproving Recovery and Outcomes Every Day after the ICU (IMPROVE): study protocol for a randomized controlled trial
Delirium affects nearly 70% of older adults hospitalized in the intensive care unit (ICU), and many of those will be left with persistent cognitive impairment or dementia. There are no effective and scalable r...
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Open AccessMobile critical care recovery program (m-CCRP) for acute respiratory failure survivors: study protocol for a randomized controlled trial
Patients admitted to intensive care units (ICU) with acute respiratory failure (ARF) face chronic complications that can impede return to normal daily function. A mobile, collaborative critical care model may ...
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Open AccessCognitive function, body mass index and mortality in a rural elderly Chinese cohort
Previous studies have shown that poor cognition and low body mass index were associated with increased mortality. But few studies have investigated the association between cognition and mortality across the en...
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Article
Alterations in brain structure and function in breast cancer survivors: effect of post-chemotherapy interval and relation to oxidative DNA damage
Neuroimaging studies have begun to uncover the neural substrates of cancer and treatment-related cognitive dysfunction, but the time course of these changes in the years following chemotherapy is unclear. This...
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Open AccessSelenium level and depressive symptoms in a rural elderly Chinese cohort
Selenium is considered a protective agent against free radicals through the maintenance of better enzyme activity. The few studies examining the relationship between selenium and depression have yielded incons...
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Article
Open AccessThe ACTIVE cognitive training trial and predicted medical expenditures
Health care expenditures for older adults are disproportionately high and increasing at both the individual and population levels. We evaluated the effects of the three cognitive training interventions (memory...
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Article
Senile dementia associated with amyloid β protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-ε4 allele
Amyloid β protein deposition in cortical and leptomeningeal vessels, causing the most common type of cerebral amyloid angiopathy, is found in sporadic and familial Alzheimer’s disease (AD) and is the principa...
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Article
The Dementing Disorders
Dementing disorders are found most commonly in the elderly. However, the approaches derived from the diagnosis and management of these patients exemplify principles which can equally well be applied to the man...
