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  1. Article

    Open Access

    Stable Response and Sustained Improvement of Itch and Sleep Symptoms in Patients with Atopic Dermatitis Treated with Lebrikizumab over 52 Weeks

    Lebrikizumab demonstrated significant improvement versus placebo for measures of skin clearance and patient-reported outcomes at weeks 16 and 52 in patients with moderate-to-severe atopic dermatitis (AD). We r...

    Gil Yosipovitch, Peter Lio, Franz J. Legat, Raj Chovatiya… in Dermatology and Therapy (2024)

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    Article

    Topical liposomal DNA-repair enzymes in polymorphic light eruption

    Polymorphic light eruption (PLE) is a very frequent photodermatosis in Europe whose pathogenesis may involve resistance to UV-induced immune suppression and simultaneous immune reactions against skin photoneoa...

    Angelika Hofer, Franz J. Legat… in Photochemical & Photobiological Sciences (2011)

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    Article

    Photodamage to the cutaneous sensory nerves: role in photoaging and carcinogenesis of the skin?

    Chronic exposure to ultraviolet radiation (UVR) plays a significant role in aging and carcinogenesis of the skin. Sensory nerve fibers densely innervate all layers of the skin and get in close anatomical as we...

    Franz J. Legat, Peter Wolf in Photochemical & Photobiological Sciences (2006)