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  1. Article

    Open Access

    Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease

    The use of transgenic mice displaying amyloid-β (Aβ) brain pathology has been essential for the preclinical assessment of new treatment strategies for Alzheimer’s disease. However, the properties of Aβ in such...

    Mara Zielinski, Fernanda S. Peralta Reyes, Lothar Gremer… in Nature Neuroscience (2023)

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