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  1. Article

    Open Access

    Neddylation activated TRIM25 desensitizes triple-negative breast cancer to paclitaxel via TFEB-mediated autophagy

    Paclitaxel (PTX) treatment resistance is an important factor leading to poor prognosis in triple-negative breast cancer (TNBC), therefore there is an urgent need to identify new target for combination therapy....

    Bowen Zheng, Fengyuan Qian, Xuehui Wang… in Journal of Experimental & Clinical Cancer … (2024)

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  2. Article

    Open Access

    ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway

    Breast cancer has the highest global incidence and mortality rates among all cancer types. Abnormal expression of the Annexin family has been observed in different malignant tumors, including upregulated ANXA9...

    **qian Zhou, Junyong Zhao, Tao Yan, Danrong Ye, Yuying Wang… in Cell Death & Disease (2024)

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  3. No Access

    Article

    The Ubiquitin Ligase COP1 Promotes Glioma Cell Proliferation by Preferentially Downregulating Tumor Suppressor p53

    Human glioma causes substantial morbidity and mortality worldwide. However, the molecular mechanisms underlying glioma progression are still largely unknown. COP1 (constitutively photomorphogenic 1), an E3 ubi...

    Shenshan Zou, Yufu Zhu, Bin Wang, Fengyuan Qian, **ang Zhang… in Molecular Neurobiology (2017)

  4. No Access

    Article

    Jab1 promotes glioma cell proliferation by regulating Siah1/β-catenin pathway

    Jab1 (Jun activation domain-binding protein 1), also known as CSN5 (COP9 signalosome subunit 5), is frequently overexpressed in several cancer types. However, the biological functions and the molecular mechani...

    Yufu Zhu, Zhichao Qiu, **ang Zhang, Fengyuan Qian, Bin Wang… in Journal of Neuro-Oncology (2017)