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  1. Article

    Open Access

    Novel circulating tumor cell-based blood test for the assessment of PD-L1 protein expression in treatment-naïve, newly diagnosed patients with non-small cell lung cancer

    We evaluated the analytical and clinical performance of a novel circulating tumor cell (CTC)-based blood test for determination of programmed death ligand 1 (PD-L1) protein expression status in real time in tr...

    Yen-Lin Chen, Wen-Chien Huang, Feng-Ming Lin in Cancer Immunology, Immunotherapy (2019)

  2. Article

    Open Access

    Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation

    SUMO post-translational modification of proteins or SUMOylation ensures normal cell function. Disruption of SUMO dynamics prompts various pathophysiological conditions, including cancer. The burden of deSUMOyl...

    Samaneh Karami, Feng-Ming Lin, Santosh Kumar, Shaymaa Bahnassy in Scientific Reports (2017)

  3. No Access

    Chapter

    Evidence-based Anticancer Materia Medica for Prostate Cancer

    Prostate cancer is a leading cause of cancer death in men in Western countries. Although progress has been made in therapies for cases where there is early diagnosis and disease is localized, current therapies...

    Yi-Ren Chen, Pei-Wen Hsiao, Feng-Ming Lin in Materia Medica for Various Cancers (2012)

  4. No Access

    Article

    Tying SUMO modifications to dynamic behaviors of chromosomes during meiotic prophase of Saccharomyces cerevisiae

    In budding yeast Saccharomyces cerevisiae, centromeres and telomeres are tethered to the nuclear envelope during premeiotic interphase. Immediately after cells enter meiotic prophase, chromosomes undergo global r...

    Chun-Hsu Cheng, Feng-Ming Lin, Yu-Hui Lo, Ting-Fang Wang in Journal of Biomedical Science (2007)