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Article
The significance of Ki-67, BrdU and OKT9 expression in determination of myelodysplastic syndromes by use of APAAP technique
Monoclonal antibodies (McAb) to Ki-67, BrdU and OKT9 were used in APAAP technique for determining the proliferative cells of 46 myelodysplastic syndromes (MDS) with 16 serving as normal controls. According to Ki-...
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Article
Determination of blood flow in the lower leg of patients with diabetes mellitus and the effects of treatment with the principle of vitalizing blood and solubilizing thrombus
Blood flow in the lower leg was determined in 50 cases of non-insulin dependent diabetes mellitus using an XLJ-2 bipolar rheoencephalometry impedance rheogram. In patients with leg pain (85 legs) and diabetic ...
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Article
Treatment with phytoestrogen α-zearalanol might protect neurons of hippocampus in ovariectomized rats
Although neuroprotective effects of estrogen on postmenopausal women have been recognized, an associated increased incidence of uterine and breast tumors has jeopardized the clinical use of estrogen. This stud...
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Article
Open AccessValue of serum glycated albumin and high-sensitivity C-reactive protein levels in the prediction of presence of coronary artery disease in patients with type 2 diabetes
Coronary artery disease (CAD) is a major vascular complication of diabetes mellitus and reveals high mortality. Up to 30% of diabetic patients with myocardial ischemia remain asymptomatic and are associated wi...
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Article
Protective effects of phytoestrogen α-zearalanol on beta amyloid25–35 induced oxidative damage in cultured rat hippocampal neurons
Although experimental evidence has shown that the neuroprotective effect from estrogen may benefit postmenopausal women, but the clinical use of estrogen was limited by the risk of increasing the cases of mamm...
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Chapter and Conference Paper
Ecdysterone attenuates vasospasm following experimental subarachnoid haemorrhage in rabbits
Cerebral vasospasm (CVS) remains a severe complication after subarachnoid haemorrhage (SAH), and there are not adequate medical treatments for it. Our previous study showed that ecdysterone might prevent CVS f...
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Article
The effectiveness of lamivudine in preventing hepatitis B viral reactivation in rituximab-containing regimen for lymphoma
In rituximab-containing regimen for lymphoma, the role of lamivudine therapy has not been well established. Therefore, in this nonrandomized phase II clinical study, hepatitis B virus (HBV) carriers with B-cel...
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Article
Phase II study of capecitabine and cisplatin combination as first-line chemotherapy in Chinese patients with metastatic nasopharyngeal carcinoma
Cisplatin combined with 5-fluorouracil (5-Fu) is widely used in the management of advanced nasopharyngeal carcinoma (NPC). However, catheters and pumps are necessary for the continuous infusion of 5-Fu, which ...
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Article
Open AccessRetrospective study of adenovirus in autopsied pulmonary tissue of pediatric fatal pneumonia in South China
Adenovirus are the important pathogen of pediatric severe pneumonia. The aim of this study is to analyze the infection, subtype and distribution of adenovirus in autopsied pulmonary tissue of fatal pneumonia i...
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Article
Effect of Jianpi Huoxue decoction (健脾活血方)-containing serum on tumor necrosis factor-α secretion and gene Expression of endotoxin receptors in RAW264.7 cells induced by lipopolysaccharide
To evaluate the effect of Jianpi Huoxue decoction (健脾活血方, JHD)-containing serum on tumor necrosis factor-α (TNF-α) secretion and endotoxin receptor gene expression in RAW264.7 cells induced by lipopolysacchari...
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Article
Effects of Danggui Buxue Decoction (当归补血汤) on lipid peroxidation and MMP-2/9 activities of fibrotic liver in rats
To explore the mechanism of Danggui Buxue Decoction (当归补血汤, DBD) on the liver fifibrosis related to hepatic lipid peroxidation and matrix metalloproteinases (MMP) −2/9 activities.
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Article
The association of HLA-B*27 subtypes with ankylosing spondylitis in Wuhan population of China
The aim of this study was to investigate the association of the B27 subtypes with ankylosing spondylitis (AS) in the Wuhan population of China. We selected 317 HLA-B27-positive individuals (145 controls and 17...
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Article
Open AccessKikuchi Fujimoto disease associated with cryptogenic organizing pneumonia: case report and literature review
The association of Kikuchi Fujimoto disease (KFD) with cryptogenic organizing pneumonia (COP) is extremely rare. We report a case of simultaneous diagnosis of KFD and COP.
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Article
Phase II study of capecitabine plus oxaliplatin (XELOX) as first-line treatment and followed by maintenance of capecitabine in patients with metastatic colorectal cancer
The aim of this study is to evaluate the safety and efficacy of the combination of capecitabine and oxaliplatin (XELOX) as first-line treatment in Chinese patients with metastatic colorectal carcinoma (mCRC). ...
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Article
High frequencies of HLA-B27 in Chinese patients with suspected of ankylosing spondylitis
This study was performed to investigate the frequency of human leukocyte antigen (HLA)-B27 in Chinese patients with suspected of ankylosing spondylitis (AS) and to assess the clinical significance of HLA-B27 t...
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Article
Alcohol and tea consumption in relation to the risk of nasopharyngeal carcinoma in Guangdong, China
To investigate whether alcohol and tea consumption has an etiological association with nasopharyngeal carcinoma (NPC) in a high-incident population, a large scale case-control study was conducted. The study in...
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Article
Effect of three suture lines on the proliferation and cell cycle of lung adenocarcinoma cell A549 in vitro
The interaction of cell and medical biomaterial is one of the significant factors to affect clinical application of medical biomaterial. This research is to investigate three of suture lines how to affect the ...
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Article
Programmed cell death 1 gene polymorphisms is associated with ankylosing spondylitis in Chinese Han population
Programmed cell death 1 (PD-1) has been reported to have a genetic association in several autoimmune diseases. The aim of this study was to investigate the association of PD-1 polymorphisms and haplotypes with...
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Article
Hepatocyte growth factor promotes liver regeneration induced by transfusion of bone marrow mononuclear cells in a murine acute liver failure model
Bone marrow mononuclear cell (BMMC) transplantation has been shown to facilitate tissue and organ regeneration and repair. BMMC transplantation may be a potential therapy for acute liver failure, and its effec...
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Article
A relationship between ABO blood groups and clinicopathologic characteristics of patients with gastric adenocarcinoma in China
Little is known about the relationship between ABO blood groups and the clinicopathologic features in gastric adenocarcinoma patients of China. Whether the distribution of ABO blood groups in patients with gas...