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Article
Open AccessIntra-tidal PaO2 oscillations associated with mechanical ventilation: a pilot study to identify discrete morphologies in a porcine model
Within-breath oscillations in arterial oxygen tension (PaO2) can be detected using fast responding intra-arterial oxygen sensors in animal models. These PaO2 signals, which rise in inspiration and fall in expirat...
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Article
Open AccessBedside monitoring of lung volume available for gas exchange
Bedside measurement of lung volume may provide guidance in the personalised setting of respiratory support, especially in patients with the acute respiratory distress syndrome at risk of ventilator-induced lun...
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Article
Physiological dead space ventilation, disease severity and outcome in ventilated patients with hypoxaemic respiratory failure due to coronavirus disease 2019
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Article
Open AccessReal-time effects of PEEP and tidal volume on regional ventilation and perfusion in experimental lung injury
Real-time bedside information on regional ventilation and perfusion during mechanical ventilation (MV) may help to elucidate the physiological and pathophysiological effects of MV settings in healthy and injur...
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Article
Open AccessDynamic single-slice CT estimates whole-lung dual-energy CT variables in pigs with and without experimental lung injury
Dynamic single-slice CT (dCT) is increasingly used to examine the intra-tidal, physiological variation in aeration and lung density in experimental lung injury. The ability of dCT to predict whole-lung values ...
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Article
Open AccessRespiratory oscillations in alveolar oxygen tension measured in arterial blood
Arterial oxygen partial pressure can increase during inspiration and decrease during expiration in the presence of a variable shunt fraction, such as with cyclical atelectasis, but it is generally presumed to ...
