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Chapter
Mechanical Characterization of Additive Manufactured Polymeric Scaffolds for Tissue Engineering
In the last decades, tissue engineering has become a promising and important field of research that is opening new perspectives for the treatment of tissue diseases or injuries. Scaffold-guided tissue engineer...
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Protocol
Computer-Aided Wet-Spinning
Computer-aided wet-spinning (CAWS) has emerged in the past few years as a hybrid fabrication technique coupling the advantages of additive manufacturing in controlling the external shape and macroporous struct...
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Article
Chitosan films for regenerative medicine: fabrication methods and mechanical characterization of nanostructured chitosan films
Regenerative medicine is continuously facing new challenges and it is searching for new biocompatible, green/natural polymer materials, possibly biodegradable and non-immunogenic. Moreover, the critical import...
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Article
Impacts of ocean acidification on carboxylated carbon nanotube effects induced in the clam species Ruditapes philippinarum
Although the increased production of nanoparticles (NPs) has raised extensive concerns about the potential toxic effects on aquatic organisms, as well as the increasing evidences which documented the impact of...
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Article
Open AccessThe influence of salinity on the effects of Multi-walled carbon nanotubes on polychaetes
Salinity shifts in estuarine and coastal areas are becoming a topic of concern and are one of the main factors influencing nanoparticles behaviour in the environment. For this reason, the impacts of multi-wall...
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Article
Open AccessNeurotrophin-conjugated nanoparticles prevent retina damage induced by oxidative stress
Glaucoma and other optic neuropathies are characterized by a loss of retinal ganglion cells (RGCs), a cell layer located in the posterior eye segment. Several preclinical studies demonstrate that neurotrophins...
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Article
Open AccessMagnetic nanoparticles: a strategy to target the choroidal layer in the posterior segment of the eye
Despite the higher rate of blindness due to population aging, minimally invasive and selective drug delivery to the eye still remains an open challenge, especially in the posterior segment. The retina, the ret...
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Article
Levofloxacin-loaded star poly(ε-caprolactone) scaffolds by additive manufacturing
The employment of a tissue engineering scaffold able to release an antimicrobial agent with a controlled kinetics represents an effective tool for the treatment of infected tissue defects as well as for the pr...
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Article
Chitosan Nanoparticles for the Linear Release of Model Cationic Peptide
The present study is focused on the development of a model drug delivery system (DDS) based on Chitosan (CS) nanoparticles using Renin substrate I (RSI) as model agent. RSI shares the main chemical-physical fe...
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Article
Tailored One-Way and Two-Way Shape Memory Capabilities of Poly(ε-Caprolactone)-Based Systems for Biomedical Applications
This paper investigates the shape memory capabilities of semicrystalline networks, focusing the attention on poly(ε-caprolactone) (PCL) systems, a class of materials that allows to satisfy important requiremen...
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Article
Preparation and characterization of hybrid nanoparticles based on chitosan and poly(methacryloylglycylglycine)
The present work investigated the possibility of preparing nanoparticles based on methacryloylglycylglycine (MAGG) and chitosan (CS) by in situ polymerization. The study revealed that nanoparticle formation wa...
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Article
Additive manufacturing of wet-spun polymeric scaffolds for bone tissue engineering
An Additive Manufacturing technique for the fabrication of three-dimensional polymeric scaffolds, based on wet-spinning of poly(ε-caprolactone) (PCL) or PCL/hydroxyapatite (HA) solutions, was developed. The pr...
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Article
Novel electrospun polyurethane/gelatin composite meshes for vascular grafts
Novel polymeric micro-nanostructure meshes as blood vessels substitute have been developed and investigated as a potential solution to the lack of functional synthetic small diameter vascular prosthesis. A com...
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Article
Porous scaffolds of polycaprolactone reinforced with in situ generated hydroxyapatite for bone tissue engineering
Polycaprolactone/hydroxyapatite (PCL/HA) composites were prepared by in situ generation of HA in the polymer solution starting from the precursors calcium nitrate tetrahydrate and ammonium dihydrogen phosphate...
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Article
Thermal analysis of PVA/CNTs 2D membrane
In the present study polymeric membranes consisting of poly(vinyl alcohol) (PVA) and multi-walled carbon nanotubes (MWCNTs) were prepared by casting method and their morphological, thermal and de-swelling beha...
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Chapter
Chitosan-Based Beads for Controlled Release of Proteins
Chitosan is biocompatible polymer of natural origin widely investigated for applications in drug delivery and regenerative medicine. In this paper, Chitosan’s capability of forming water gelling beads in the p...
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Chapter
Hybrid Hydrogels Based on Poly(vinylalcohol)-Chitosan Blends and Relevant CNT Composites
The present paper reports on the preparation of hybrid polymeric hydrogels consisting of poly(vinylalcohol) (PVA) and Chitosan (CHI) blends and relevant composites loaded with multiwalled carbon nanotubes (MWC...
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Chapter and Conference Paper
Biobased Polymeric Materials for Agriculture Applications
Owing to their low production cost, good physical properties and lightweight, plastic objects have slowly substituted glass, paper and metals in several fields of application including agriculture. Polymeric m...
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Chapter
Polymeric Hydrogels in Drug Release
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Article
Molecular Interactions and Inclusion Phenomena in Substituted β-Cyclodextrins. Simple Inclusion Probes: H2O, C, CH4, C6H6, NH4 +, HCOO−
Using a simple molecular mechanics approach interaction energy profiles of simple probes (C, CH4, C6H6, H2O, NH4 +, and HCOO-) passing through the center of the β-CD ring cavity along the main molecular symmetry ...
