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Article

CSF biomarker analysis of ABCA7 mutation carriers suggests altered APP processing and reduced inflammatory response

The Alzheimer’s disease (AD) risk gene ABCA7 has suggested functions in lipid metabolism and the immune system. Rare premature termination codon (PTC) mutations and an expansion of a variable number of tandem rep...

Lena Duchateau, Fahri Küҫükali, Arne De Roeck… in Alzheimer's Research & Therapy (2023)