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Article
Open AccessAdipocytes reprogram prostate cancer stem cell machinery
It is now well-established that an obese condition correlates with a higher risk of prostate cancer (PCa). A crosstalk between adipose tissue and PCa has been observed but is still poorly characterized. Herein...
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Article
Open AccessCa2+ overload- and ROS-associated mitochondrial dysfunction contributes to δ-tocotrienol-mediated paraptosis in melanoma cells
Melanoma is an aggressive tumor with still poor therapy outcomes. δ-tocotrienol (δ-TT) is a vitamin E derivative displaying potent anti-cancer properties. Previously, we demonstrated that δ-TT triggers apoptos...
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Article
Open AccessDual role of autophagy on docetaxel-sensitivity in prostate cancer cells
Prostate cancer (PC) is one of the leading causes of death in males. Available treatments often lead to the appearance of chemoresistant foci and metastases, with mechanisms still partially unknown. Within tum...
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Article
Open AccessTargeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol
The prognosis of metastatic melanoma is very poor, due to the development of drug resistance. Cancer stem cells (CSCs) may play a crucial role in this mechanism, contributing to disease relapse. We first chara...
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Chapter and Conference Paper
Multidisciplinary Education in Managing Maxi-Health Emergencies in Unconventional Events: Preliminary Results from the International Security/Safety/Global Strategy and Medical Maxi-Emergency (ISSMMdelta) Master
In a globalized world, natural, accidental catastrophes and several devastating terroristic events destroyed our perceived social security, thus stimulating the European Community to issue a specific directive...
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Chapter and Conference Paper
Best Practices in Nuclear Medicine
Nowadays, CBRN risks represent a serious problem that is taken under consideration in many countries. The strict monitoring of the internal situation in our cities cannot definitely avoid undesired terroristic...
