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    Effect of liposome-entrapped methotrexate on ehrlich ascites tumor cells and uptake in primary liver cell tumor

    A therapeutically useful concentration (0,5 mg/ml) of Methotrexate was prepared in negatively charged artificial liposomes (lecithine: cholesterol: dicetylphosphate=5:5:1 molar ratios). Entrapment yield after ...

    J. Freise, F. W. Schmidt, P. Magerstedt in Journal of Cancer Research and Clinical Oncology (1979)