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Chapter
Conservative Clinical Treatment of Acute Liver Failure
Fulminant hepatic failure may occur suddenly in the course of various liver diseases with viral hepatitis as the most common cause [17]:
Viral hepatitis (A, B, C, herpes simplex)
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Article
Pathophysiology and clinical basis of prevention and treatment of complications of chronic liver disease
Chronic liver failure is characterized by the appearance of jaundice, ascites, encephalopathy and/or gastrointestinal bleeding. Acute episodes of hepatic decompensation are frequently precipitated by additiona...
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Article
Unusually rapid development of a HBsAG-positive liver cirrhosis after liver transplantation
We report the case of a 44-year-old man who was transplanted in 1986 for hepatocellular carcinoma in a HBsAG-positive liver cirrhosis. The patient had no severe complications postoperatively. He received passi...
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Article
Effekte einer Captopriltherapie auf die Natrium- und Wasserausscheidung bei Patienten mit Leberzirrhose und Aszites
Ascites in patients with cirrhosis of the liver frequently is refractory to diuretic treatment. It was postulated that vasoconstriction of the renal cortex, mediated by activation of the renin-angiotensin-aldo...
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Chapter
Biochemical Aspects of Transplantation
The report is mainly based on own experience and, thus, virtually confined to liver transplantation (LTX). Two crucial problems are selected to demonstrate the possibilities and the limitations of clinical che...
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Chapter and Conference Paper
Effect of an ANP bolus injection on endocrine and renal regulation in patients with liver cirrhosis and ascites
Basal levels of atrial natriuretic peptide (ANP), aldosterone, renin, and vasopressin were investigated in patients with liver cirrhosis in 10 patients with ascites following a bolus injection of 33μg ANP. Thi...
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Article
Proposed routine method for phenoty** of cholinesterase (CHE) locus E1 variants with butyrylthiocholine as substrate at 37 °C
The proposed method is based on routine reagents and equipment, and gives reliable results. The three inhibitors are suited to decide, if a low CHE activity is inherited or acquired and to estimate the degree ...
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Article
Interference of adenylate kinase (AK) with creatine kinase (CK) determination in sera of patients with acute liver cell damage
The results have shown that after liver TX a considerable fraction (up to 36%) of apparent CK activity may consist of uninhibited L-AK activity. This inaccuracy can roughly be estimated by measuring a serum bl...
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Chapter
On the Position of the Determination of Bile Acids in Serum (Fasting = FBA and After a Standardized Test Meal = PPBA) in the Laboratory Diagnosis of Liver Diseases
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Bei 151 Patienten mit Leber- und Gallenwegs-Erkrankungen wurde die diagnostische Aussage der Serum-Gallensäuren-Konzent...
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Chapter
On the Recognition of Hepatotoxic Side Effects of Cyclosporin A (CyA) After Liver Transplantation (LTX)
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Das Enzym-Muster im Serum bei Cyclosporin-A-Hepatotoxicität zeigt Zeichen von LeberzellSchädigung und Cholestase. Keine...
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Article
Evaluation of the effect of variable refraction index on the path of a laser beam
The use of a laser-Doppler anemometer to measure velocities in a fluid with a larger variation in its refractive index perpendicular to the laser beams may introduce appreciable errors. This situation is commo...
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Chapter and Conference Paper
Therapie des Aszites: Ausschwemmungs- und Erhaltungstherapie, Indikationen zum peritoneovenösen Shunt
Unsere Schwierigkeiten in der Therapie des Aszites lassen sich im wesentlichen auf 3 Ursachen zurückführen:
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Die Vorstellungen ...
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Article
Präprothrombin bei akuter Virushepatitis B
In vitamin K deficiency or treatment with vitamin K antagonists, a precoagulant of prothrombin (Factor II) called preprothrombin has been established. We measured preprothrombin with Clarke-Freeman electrophor...
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Article
Intestinal lavage in the treatment of crohn's disease: A pilot study
Taking into account that a damaged mucosal barrier may be responsible for the impairment and some systemic complications in Crohn's disease, we employed intestinal lavage as a therapeutic method in six patient...
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Chapter and Conference Paper
Hämostasiologie
Die Pathogenese erworbener Thrombozytopathien ist bisher nur unzureichend aufgeklärt. Klinische Erfahrung zeigt, daß bei Patienten mit lokaler oder disseminierter intravasaler Gerinnung, wie sie z. B. im Rahme...
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Chapter and Conference Paper
Strategie-Probleme bei der Diagnostik von Leberkrankheiten
Das Modell „Herzinfarkt“ mit seinen Ja-Nein-Entscheidüngen ist gut geeignet, die Vorteile rechner-unterstützter Diagnose-Strate- gien zu demonstrieren. Das Modell „Leber-Krankheiten“ mit der Fülle seiner Möglichk...
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Chapter and Conference Paper
Auswertung von Krankheitsverläufen - Probleme und Lösungsmöglichkeiten: Dargestellt am Beispiel der akuten Virushepatitis
Bei der vergleichenden Untersuchung von Krankheitsverläufen stellt sich oft das Problem der zeitlichen Synchronisation. Seit einigen Jahren existieren mehrere Programmsysteme, die für die Auswertung von Verlau...
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Chapter
Clinical Results: Central Nervous System
Creatine kinase activity in the central nervous system is relatively high, amounting up to 200 U/g fresh tissue. This activity is almost entirely due to the CK-BB isoenzyme (for details see Chap. 12). It could...
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Chapter
Correction of Increased Plasma Amino Acid Levels by Dialysis with Amino Acid-Electrolyte-Glucose Solutions
In vitro dialysis experiments were carried out to investigate the possible use of amino-acid-electrolyte-glucose solutions to correct elevated amino acid levels in the serum of patients in hepatic failure. Ser...
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Chapter
Clinical Results: Intoxication
Differentiation of creatine kinase isoenzymes was performed with the immunoinhibition and the immunoprecipitation method, as described in Chap. 3.3. In the sera of 239 patients with exogenous intoxication of d...