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Article
Open AccessThe influence of a high fat diet on bone and soft tissue formation in Matrix Gla Protein knockout mice
Studies suggest bone growth and development are influenced by maternal nutrition, during intrauterine and early postnatal life. This study assessed the role of MGP and a maternal high fat diet on vitamin K-dep...
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Article
Open AccessMNK1 and MNK2 mediate adverse effects of high-fat feeding in distinct ways
The MAP kinase-interacting kinases (MNK1 and MNK2) are non-essential enzymes which are activated by MAP kinases. They are implicated in controlling protein synthesis. Here we show that mice in which the expres...
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Article
Maternal high-fat diet: effects on offspring bone structure
Peak bone mass is believed to partly be programmed in utero. Mouse dams and offspring were given a high-fat diet and offspring studied as adults. Female offspring from high-fat dams exhibited altered trabecula...