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Chapter and Conference Paper
Interleukins and Haematopoietic Growth Factors
One of the most challenging areas of contemporary oncological and immunological research is represented by investigation of the potential clinical use of human cytokines.
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Chapter and Conference Paper
Cytokines and Hematopoietins: Physiology, Pathophysiology, and Potential as Therapeutic Agents
Improved understanding of host biology, immunology, and tumor pathophysiology raises the possibility of introducing new treatment modalities for cancer patients: stimulation of host defense mechanisms, includi...
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Article
Pilot study for the evaluation of T-cell-mediated tumor immunotherapy by cytokine gene transfer in patients with malignant tumors
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Article
Guidelines for the design and implementation of clinical studies in somatic cell therapy and gene therapy
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Chapter and Conference Paper
Tumor Immunotherapy by IL-2 and IL-2 Gene Transfected Cells
Tumortherapy is based on a variety of treatment modalities. Directly operating cytoreductive approaches are designed to work either locally like surgery or radiotherapy, or systemically like cytotoxic drugs. O...
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Chapter and Conference Paper
Potent Presentation of Soluble Protein Antigens by In Vitro-Generated Dendritic Cells from Peripheral Blood CD34+ Progenitor Cells
Dendritic cells (DC) are potent antigen-presenting cells (APC) and thus are specifically involved in the initiation of antigen-specific immune responses. Due to their potent costimulatory activity, they are we...
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Chapter and Conference Paper
Somatic Gene Therapy in Cancer
Cancer is rapidly becoming the leading medical cause of death in Western society. Currently, the most important treatment modalities in clinical oncology are surgery, radiotherapy, and chemotherapy with cytost...
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Article
NTS influence on transgene expression from mono- and bicistronic plasmid vectors after lipofection in a human fibroblast cell line
We evaluated the survival, transgene production, and copy numbers of integrated plasmid units per host genome after lipofection with mono- and bicistronic plasmid vectors in different cell lines and under var...
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Article
Gentherapie in der Onkologie
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Chapter
Particular Treatment Procedures
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Chapter
Procédures thérapeutiques particulières
Les cellules souches hématopoïétiques sont une petite population essentiellement dormante de cellules indifférenciées. Elles sont caractérisées par leur capacité d’auto-renouvellement par division cellulaire c...