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  1. No Access

    Article

    Non-invasive ventilation in neuromuscular diseases: should we use higher levels of ventilatory support?

    In patients with COPD, one of the leading indications for domiciliary non-invasive ventilation (NIV), a major paradigm shift has been observed over the past decade in the method for adjusting NIV settings, wit...

    A. Léotard, M. Delorme, S. Hartley, C. Khouri, M. Lebret, F. Lofaso in Sleep and Breathing (2023)

  2. Article

    Open Access

    Long-term exposure to Myozyme results in a decrease of anti-drug antibodies in late-onset Pompe disease patients

    Immunogenicity of recombinant human acid-alpha glucosidase (rhGAA) in enzyme replacement therapy (ERT) is a safety and efficacy concern in the management of late-onset Pompe disease (LOPD). However, long-term ...

    Elisa Masat, Pascal Laforêt, Marie De Antonio, Guillaume Corre in Scientific Reports (2016)

  3. Article

    Open Access

    Caspase-independent apoptosis in infected macrophages triggered by sulforaphane via Nrf2/p38 signaling pathways

    Mycobacterium abscessus (Mabs), a non-tuberculous mycobacterium, is an emerging and rapidly growing opportunistic pathogen that is frequently found in patients with cystic fibrosis and in immunosuppressed patient...

    M Bonay, A-L Roux, J Floquet, Y Retory, J-L Herrmann, F Lofaso in Cell Death Discovery (2015)

  4. Article

    PCO2 transcutanée: pourquoi, comment et pour qui ?

    La mesure de la pression transcutanée en dioxyde de carbone (PtcCO2) n’est pas une technologie récente, les premiers essais remontant au début des années 1960. L’amélioration des moniteurs, la miniaturisation et ...

    P. -E. Gancel, R. Masson, D. Du Cheyron, E. Roupie, F. Lofaso, N. Terzi in Réanimation (2012)

  5. No Access

    Chapter

    Sleep breathing abnormalities in neuromuscular diseases

    In neuromuscular diseases, respiratory muscle paralysis, and the thoracic deformities which often accompany these diseases, may lead to a respiratory deficiency resulting in alveolar hypoventilation [8, 16, 21...

    M. A. Quera Salva, G. Mroue, Ph. Gajdos, J. C Raphael, F. Lofaso in Sleep (2003)

  6. Article

    Interaction between steady flow and individualised compliant segments: Application to upper airways

    R. Fodil, C. Ribreau, B. Louis, F. Lofaso in Medical and Biological Engineering and Com… (1998)

  7. No Access

    Article

    Interaction between steady flow and individualised compliant segments: Application to upper airways

    To describe upper airway obstruction in patients with sleep apnea syndrome, the steady state solutions of a simple model of local pharyngeal obstruction were studied. Importantly, the present model embodies a ...

    R. Fodil, C. Ribreau, B. Louis, F. Lofaso in Medical and Biological Engineering and Com… (1997)

  8. No Access

    Article

    Topical upper airway anaesthesia with lidocaine increases airway resistance by impairing glottic function

    To assess if two different forms of upper airway topical anaesthesia induce similar changes in airway flow resistance (Rrs).

    L. Beydon, A. -M. Lorino, F. Verra, M. Labroue, P. Catoire in Intensive Care Medicine (1995)

  9. Article

    Assessment of neonatal ventilator performances

    To analyze efficiency and reliability of 4 modern neonatal ventilators under difficult test conditions. The ventilators tested were: Babylog 8000 (Dräger Medical), BP 2001 (Bear Medical Systems), Sechrist IV 1...

    P. Jouvet, P. Hubert, P. H. Jarreau, F. Lofaso, M. Cloup in Intensive Care Medicine (1995)

  10. No Access

    Article

    Failure of the intracaval filter of Günther to prevent recurrence of pulmonary embolism — report of two cases

    Two out of nine patients in which inferior vena cava interruption was performed with a Günther filter developed a recurrent pulmonary embolism. In both cases, the filter had moved down and the anchoring legs h...

    F. Lofaso, A. A. Messadi, M. C. Anglade, Y. Huet in Intensive Care Medicine (1990)