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Article
The Blood Platelet as a Model for Regulating Blood Coagulation on Cell Surfaces and Its Consequences
Platelets actively participate in regulating thrombin production following physical or chemical injury to blood vessels. Injury to blood vessels initiates activation of the large numbers of platelets that appe...
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Chapter
Mechanisms for the Anticoagulant Effects of Synthetic Antithrombins
The important roles of thrombin in the development and propagation of thrombosis are well recognized. In addition to being the enzyme for clotting fibrinogen (the major protein component of blood clots), throm...
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Chapter and Conference Paper
Functions of von Willebrand Factor in Plasma
Von Willebrand factor (vWF) is a multimeric plasma glycoprotein with Mr of the multimers varying in size from ~1 to 20 x 106. Congenital and acquired vWF deficiency are associated with bleeding tendencies and pro...
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Article
Anticoagulant Effects of Heparin in Neonatal Plasma'
ABSTRACT: Available data on the anticoagulant effects of heparin in neonatal plasma are scarce and conflicting: relative to adult plasma, neonatal plasma has been reported to show both resistance as well as se...
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Chapter
A Human Lymphoblastoid Cell Line Secreting Antiidiotypic Antibodies
It has been postulated that antiidiotypic antibodies play an important role in maintaining tolerance in vivo, thereby enhancing allograft survival in renal transplant recipients (1–3). These antibodies have be...
