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  1. No Access

    Article

    Cytokine-induced restoration of differentiation and cell cycle arrest in v-Myc transformed U-937 monoblasts correlates with reduced Myc activity

    Deregulated expression of the myc-family of oncogenes in hematopoietic and other cell types plays an important role in tumorigenesis, and results in increased proliferative potential and block of cellular differe...

    F Öberg, S Wu, F Bahram, K Nilsson, L-G Larsson in Leukemia (2001)

  2. No Access

    Article

    The role of RAR and RXR activation in retinoid-induced tissue factor suppression

    Excessive expression of tissue factor (TF) is a common finding in leukaemic cells and may contribute to thrombotic complications in patients. Retinoic acid has been shown to induce differentiation and reduce T...

    T Tenno, J Botling, F Öberg, S Jossan, K Nilsson, A Siegbahn in Leukemia (2000)

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    Chapter

    Cytokine-induced Inhibition of Myc Activity in Monocytic Cells

    The c-myc proto-oncogene plays an important role in the regulation of cell proliferation, differentiation and apoptosis. It encodes a transcription factor of the basic region/helix-loop-helix/leucine zipper (bHLH...

    L.-G. Larsson, F. Bahram, S. Wu, F. Öberg, K. Nilsson… in C-Myc in B-Cell Neoplasia (1997)