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  1. Article

    Open Access

    Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial

    This Phase 1 study evaluates the intra- and peritumoral administration by convection enhanced delivery (CED) of human recombinant Bone Morphogenetic Protein 4 (hrBMP4) – an inhibitory regulator of cancer stem ...

    Eelke M. Bos, Elena Binda, Iris S.C. Verploegh, Eva Wembacher in Molecular Cancer (2023)