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Article
Open AccessUBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis
Osteoporosis is a condition characterized by decreased bone mineral density (BMD) and reduced bone strength, leading to an increased risk of fractures. Here, to identify novel risk variants for susceptibility ...
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Article
Open AccessConcurrent TSHR mutations and DIO2 T92A polymorphism result in abnormal thyroid hormone metabolism
Deiodinase 2 (DIO2) plays an important role in thyroid hormone metabolism and its regulation. However, molecular mechanism that regulates DIO2 activity remains unclear; only mutaions in selenocysteine insertio...