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Chapter and Conference Paper
DESA: Decentralized Self-adaptive Horizontal Autoscaling for Bursts of Load in Fog Computing
With the increase of Web of Things devices, fog computing has emerged as a promising solution to lower the communication overhead and congestion in the cloud. In fog computing systems, microservices are deploy...
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Article
Open AccessNANOG confers resistance to complement-dependent cytotoxicity in immune-edited tumor cells through up-regulating CD59
Cancer immunoediting drives the adaptation of tumor cells to host immune surveillance. Previously, we have demonstrated that immunoediting driven by cytotoxic T lymphocytes (CTLs) enriches NANOG+ tumor cells with...
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Article
Open AccessTargeting TCTP sensitizes tumor to T cell-mediated therapy by reversing immune-refractory phenotypes
Immunotherapy has emerged as a powerful approach to cancer treatment. However, immunotherapeutic resistance limits its clinical application. Therefore, identifying immune-resistant factors, which can be target...
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Chapter and Conference Paper
DNN Model Deployment on Distributed Edges
Deep learning-based visual analytic applications have drawn attention by suggesting fruitful combinations with Deep Neural Network (DNN) models and visual data sensors. Because of the high cost of DNN inferenc...
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Chapter and Conference Paper
PASTA: An Efficient Proactive Adaptation Approach Based on Statistical Model Checking for Self-Adaptive Systems
Proactive adaptation, in which the adaptation for a system’s reliable goal achievement is performed by predicting changes in the environment, is considered as an effective alternative to reactive adaptation, i...
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Article
Open AccessHSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors
Cancer immunotherapy has emerged as a promising cancer treatment. However, the presence of immune-refractory tumor cells limits its clinical success by blocking amplification of anti-tumor immunity. Previously...
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Article
Open AccessEpidermal growth factor expression as a predictor of chemotherapeutic resistance in muscle-invasive bladder cancer
Epidermal growth factor receptor (EGFR) overexpression is believed to be associated with bladder cancer (BC) progression and poor clinical outcomes. In vivo studies have linked EGFR subcellular trafficking and...
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Article
Open AccessMenthol, a unique urinary volatile compound, is associated with chronic inflammation in interstitial cystitis
Chronic inflammation is a potential systemic risk factor for many bladder dysfunctions, including interstitial cystitis (IC). However, the underlying mechanism through which a healthy bladder protects itself f...
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Article
Open AccessAuthor Correction: Alpha-oxoglutarate inhibits the proliferation of immortalized normal bladder epithelial cells via an epigenetic switch involving ARID1A
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
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Article
Open AccessAlpha-oxoglutarate inhibits the proliferation of immortalized normal bladder epithelial cells via an epigenetic switch involving ARID1A
Interstitial cystitis (IC) is a chronic urinary tract disease that is characterized by unpleasant sensations, such as persistent pelvic pain, in the absence of infection or other identifiable causes. We previo...
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Article
Open AccessInterstitial Cystitis-Associated Urinary Metabolites Identified by Mass-Spectrometry Based Metabolomics Analysis
This study on interstitial cystitis (IC) aims to identify a unique urine metabolomic profile associated with IC, which can be defined as an unpleasant sensation including pain and discomfort related to the uri...
