Skip to main content

and
  1. Article

    Open Access

    Understanding the molecular basis of anorexia and tissue wasting in cancer cachexia

    Cancer cachexia syndrome is a major cause of morbidity and mortality in cancer patients in the advanced stage. It is a devastating disorder characterized by nutritional impairment, weakness, and wasting, and i...

    Eunbyul Yeom, Kweon Yu in Experimental & Molecular Medicine (2022)

  2. Article

    Tumour-derived Dilp8/INSL3 induces cancer anorexia by regulating feeding neuropeptides via Lgr3/8 in the brain

    In patients with advanced-stage cancer, cancer-associated anorexia affects treatment success and patient survival. However, the underlying mechanism is poorly understood. Here, we show that Dilp8, a Drosophila ho...

    Eunbyul Yeom, Hyemi Shin, Wonbeak Yoo, Eunsung Jun, Seokho Kim in Nature Cell Biology (2021)

  3. Article

    Open Access

    Ciao1 interacts with Crumbs and Xpd to regulate organ growth in Drosophila

    Ciao1 is a component of the cytosolic iron–sulfur cluster assembly (CIA) complex along with MMS19 and MIP18. Xeroderma pigmentosum group D (XPD), a DNA helicase involved in regulation of cell cycle and transcr...

    Jean Jung, Eunbyul Yeom, Kwang-Wook Choi in Cell Death & Disease (2020)