4 Result(s)

Article

Spatiotemporal characterization of glial cell activation in an Alzheimer’s disease model by spatially resolved transcriptomics

The molecular changes that occur with the progression of Alzheimer’s disease (AD) are well known, but an understanding of the spatiotemporal heterogeneity of changes in the brain is lacking. Here, we investiga...

Hongyoon Choi, Eun Ji Lee, ** Seop Shin, Hyun Kim… in Experimental & Molecular Medicine (2023)

Article

Reduced expression of TAZ inhibits primary cilium formation in renal glomeruli

Renal primary cilia are antenna-like organelles that maintain cellular homeostasis via multiple receptors clustered along their membranes. Recent studies have revealed that YAP/TAZ, key paralogous effectors of...

Jae Hee Jun, Eun Ji Lee, Minah Park, Je Yeong Ko… in Experimental & Molecular Medicine (2022)

Article

Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases

The endoplasmic reticulum (ER) is not only important for protein synthesis and folding but is also crucial for lipid synthesis and metabolism. In the current study, we demonstrate an important role of ceramide...

Ye-Ryung Kim, Eun-Ji Lee, Kyong-Oh Shin, Min Hee Kim… in Experimental & Molecular Medicine (2019)

Article

Special issue on protein acetylation: from molecular modification to human disease

Eun ji Lee, Ji Hae Seo, Kyu-Won Kim in Experimental & Molecular Medicine (2018)