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Article
Synthesis of bioadhesive PHEA hydrogels without crosslinkers through in situ polymerization and sustained mechanical mixing
This study presents a novel methodology for the fabrication of bioadhesives composed of poly(2-hydroxyethyl acrylate) (PHEA), which demonstrate superior mechanical properties. Hydrogels based on PHEA were effe...
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Article
Comparative study on the rheological properties of natural and synthetic graphite-based anode slurries for lithium-ion batteries
The rheological behavior of anode slurries for lithium-ion batteries, containing both natural and synthetic graphite as active material, was investigated with a focus on the different graphite morphologies. Wh...
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Article
Anti-tumor effect of CDK inhibitors on CDKN2A-defective squamous cell lung cancer cells
Squamous cell lung cancer (SqCLC) is a distinct histologic subtype of non-small cell lung cancer (NSCLC). Although the discovery of driver mutations and their targeted drugs has remarkably improved the treatme...
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Article
Gefitinib induces cytoplasmic translocation of the CDK inhibitor p27 and its binding to a cleaved intermediate of caspase 8 in non-small cell lung cancer cells
The epidermal growth factor receptor (EGFR) represents one of the first rationally selected molecules for targeted therapy in non-small cell lung cancer (NSCLC). Gefitinib is a reversible and highly selective ...
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Article
Open AccessOverexpression of Snail is associated with lymph node metastasis and poor prognosis in patients with gastric cancer
Epithelial–mesenchymal transition (EMT) plays a significant role in tumor progression and invasion. Snail is a known regulator of EMT in various malignant tumors. This study investigated the role of Snail in g...
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Article
Carcinosarcoma of the gallbladder: report of two cases
Adenocarcinoma is the predominant histological type of carcinoma of the gallbladder, accounting for more than 80% of all gallbladder carcinomas. In contrast, carcinosarcoma of the gallbladder is an extremely a...