4 Result(s)

Article

Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring

Blood biomarkers indicative of Alzheimer’s disease (AD) pathology are altered in both preclinical and symptomatic stages of the disease. Distinctive biomarkers may be optimal for the identification of AD patho...

Nicholas J. Ashton, Shorena Janelidze, Niklas Mattsson-Carlgren… in Nature Medicine (2022)

Article

Bioinformatics tools and data resources for assay development of fluid protein biomarkers

Fluid protein biomarkers are important tools in clinical research and health care to support diagnosis and to monitor patients. Especially within the field of dementia, novel biomarkers could address the curre...

Katharina Waury, Eline A. J. Willemse, Eugeen Vanmechelen… in Biomarker Research (2022)

Article

Publisher Correction: Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer’s disease

Marta Milà-Alomà, Nicholas J. Ashton, Mahnaz Shekari, Gemma Salvadó… in Nature Medicine (2022)

Article

Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer’s disease

Blood biomarkers indicating elevated amyloid-β (Aβ) pathology in preclinical Alzheimer’s disease are needed to facilitate the initial screening process of participants in disease-modifying trials. Previous bio...

Marta Milà-Alomà, Nicholas J. Ashton, Mahnaz Shekari, Gemma Salvadó… in Nature Medicine (2022)