4 Result(s)
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Article
Open AccessSpatially aware clustering of ion images in mass spectrometry imaging data using deep learning
Computational analysis is crucial to capitalize on the wealth of spatio-molecular information generated by mass spectrometry imaging (MSI) experiments. Currently, the spatial information available in MSI data ...
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Article
Open AccessCytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells
The 78-kDa glucose-regulated protein (GRP78) is an ubiquitously expressed endoplasmic reticulum chaperone, with a central role in maintaining protein homeostasis. Recently, an alternative role for GRP78 under ...
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Article
Identification of PP2A/Set Binding Sites and Design of Interacting Peptides with Potential Clinical Applications
Protein phosphatase 2A (PP2A) is known to be a negative regulator of several survival and proliferating pathways that are frequently altered in cancer. In addition to chemical enzymatic inhibitors of the PP2A ...
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Article
Venom components from Citharischius crawshayi spider (Family Theraphosidae): exploring transcriptome, venomics, and function
Despite strong efforts, knowledge about the composition of the venom of many spider species remains very limited. This work is the first report of transcriptome and venom analysis of the African spider Citharisch...
