6 Result(s)

Article

SMURF1 silencing diminishes a CD44-high cancer stem cell-like population in head and neck squamous cell carcinoma

Bone morphogenetic protein (BMP) signaling is thought to play key roles in regulating the survival and maintenance of cancer stem cells (CSCs), which contribute to disease recurrences and treatment failures in...

Ali Khammanivong, Raj Gopalakrishnan, Erin B Dickerson in Molecular Cancer (2014)

Article

Lysosomal drug sequestration as a mechanism of drug resistance in vascular sarcoma cells marked by high CSF-1R expression

Human angiosarcoma and canine hemangiosarcoma are thought to arise from vascular tissue or vascular forming cells based upon their histological appearance. However, recent evidence indicates a hematopoietic or...

Brandi H Gorden, Jhuma Saha, Ali Khammanivong, Gary K Schwartz… in Vascular Cell (2014)

Article

Hemangiosarcoma and its cancer stem cell sub-population are effectively killed by a toxin targeted through epidermal growth factor and urokinase receptors

Jill T Schappa, Aric M Frantz, Brandi H Gorden, Erin B Dickerson… in BMC Proceedings (2013)

Article

Constitutive expression and roles of interleukin-8 in canine hemangiosarcoma

Jong-Hyuk Kim, Katie L Anderson, Aric M Frantz, Ashley J Graef… in BMC Proceedings (2013)

Article

Chemosensitization of cancer cells by siRNA using targeted nanogel delivery

Chemoresistance is a major obstacle in cancer treatment. Targeted therapies that enhance cancer cell sensitivity to chemotherapeutic agents have the potential to increase drug efficacy while reducing toxic eff...

Erin B Dickerson, William H Blackburn, Michael H Smith, Laura B Kapa… in BMC Cancer (2010)

Article

Identification of candidate methylation-responsive genes in ovarian cancer

Aberrant methylation of gene promoter regions has been linked to changes in gene expression in cancer development and progression. Genes associated with CpG islands (CGIs) are especially prone to methylation, ...

Laura Menendez, DeEtte Walker, Lilya V Matyunina, Erin B Dickerson… in Molecular Cancer (2007)