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Open AccessSMURF1 silencing diminishes a CD44-high cancer stem cell-like population in head and neck squamous cell carcinoma
Bone morphogenetic protein (BMP) signaling is thought to play key roles in regulating the survival and maintenance of cancer stem cells (CSCs), which contribute to disease recurrences and treatment failures in...
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Open AccessChemosensitization of cancer cells by siRNA using targeted nanogel delivery
Chemoresistance is a major obstacle in cancer treatment. Targeted therapies that enhance cancer cell sensitivity to chemotherapeutic agents have the potential to increase drug efficacy while reducing toxic eff...
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Article
Open AccessIdentification of candidate methylation-responsive genes in ovarian cancer
Aberrant methylation of gene promoter regions has been linked to changes in gene expression in cancer development and progression. Genes associated with CpG islands (CGIs) are especially prone to methylation, ...