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  1. Article

    Open Access

    Epistasis between FLG and IL4R Genes on the Risk of Allergic Sensitization: Results from Two Population-Based Birth Cohort Studies

    Immune-specific genes as well as genes responsible for the formation and integrity of the epidermal barrier have been implicated in the pathogeneses of allergic sensitization. This study sought to determine wh...

    Ali H. Ziyab, Jenny Hankinson, Susan Ewart, Eric Schauberger… in Scientific Reports (2018)

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  2. No Access

    Article

    Lipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic Targets

    Bioactive lipids are critical regulators of inflammation. Over the last 75 years, these diverse compounds have emerged as clinically-relevant mediators of allergic disease pathophysiology. Animal and human stu...

    Eric Schauberger, Miriam Peinhaupt, Tareian Cazares… in Current Allergy and Asthma Reports (2016)

  3. Article

    Open Access

    The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

    The occurrence of asthma is weakly explained by known genetic variants. Epigenetic marks, DNA methylation (DNA-M) in particular, are considered to add to the explanation of asthma. However, no etiological mode...

    Nelís Soto-Ramírez, Syed Hasan Arshad, John W Holloway… in Clinical Epigenetics (2013)

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