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    Chapter

    Microvascular Structural Alterations and Tissue Perfusion in Hypertension/Diabetes

    The development of structural changes in the systemic vasculature is the end result of established hypertension. Indeed, in essential hypertension, small arteries smooth muscle cell are restructured around a s...

    Damiano Rizzoni, Carolina De Ciuceis in Prehypertension and Cardiometabolic Syndro… (2019)

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    Article

    Microvascular Density and Circulating Endothelial Progenitor Cells Before and After Treatment with Incretin Mimetics in Diabetic Patients

    Glucagon-like peptide 1-receptor agonists (incretin mimetics) and dipeptidyl peptidase-4 inhibitors (incretin enhancers) have been recently introduced in the treatment of diabetes mellitus. In particular, incr...

    Carolina De Ciuceis, Claudia Agabiti-Rosei in High Blood Pressure & Cardiovascular Preve… (2018)

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    Article

    Use of Antihypertensive Drugs in Neoplastic Patients

    The introduction of Vascular Endothelial Growth Factor (VEGF) signaling pathway inhibitor treatment has highlighted the role of the baseline activity of the VEFG system for blood pressure regulation. VEGF sign...

    Damiano Rizzoni, Carolina De Ciuceis in High Blood Pressure & Cardiovascular Preve… (2017)

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    Article

    Immune Mechanisms in Hypertension

    Low grade inflammation may have a key role in the pathogenesis of hypertension and cardiovascular disease. Several studies showed that both innate and adaptive immune systems may be involved, being T cells the...

    Carolina De Ciuceis, Claudia Rossini in High Blood Pressure & Cardiovascular Preve… (2014)

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    Article

    How to Assess Microvascular Structure in Humans

    Structural alterations of subcutaneous small resistance arteries, as indicated by an increased media to lumen ratio, are frequently present in hypertensive and/or diabetic patients. However, the evaluation of ...

    Professor Damiano Rizzoni in High Blood Pressure & Cardiovascular Preve… (2011)

  6. Article

    Open Access

    Intracellular molecular effects of insulin resistance in patients with metabolic syndrome

    Patients with metabolic syndrome (MetS) have an increased risk of cardiovascular disease. Data obtained from muscle biopsies have demonstrated altered insulin signaling (IS) in patients with MetS. The IS regul...

    Evasio Pasini, Vincenzo Flati, Silvia Paiardi in Cardiovascular Diabetology (2010)

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    Article

    Coronary Flow Reserve and Small Artery Remodelling in Hypertensive Patients

    Objective: To evaluate the relationship between subcutaneous small arteries structure and coronary flow reserve in patients with essential hypertension.

    Dr Damiano Rizzoni, Carlo Palombo in High Blood Pressure & Cardiovascular Preve… (2008)

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    Article

    Remodelling of Small Resistance Arteries in Essential Hypertension

    Regardless of the mechanisms that initiate the rise of blood pressure, the development of structural changes in the systemic vasculature is the end result of established hypertension. In essential hypertension...

    Carolina De Ciuceis, Damiano Rizzoni in High Blood Pressure & Cardiovascular Preve… (2006)