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Enrico Agabiti Rosei
Cardiology
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Article
Open AccessThe Results of the URRAH (Uric Acid Right for Heart Health) Project: A Focus on Hyperuricemia in Relation to Cardiovascular and Kidney Disease and its Role in Metabolic Dysregulation
The relationship between Serum Uric Acid (UA) and Cardiovascular (CV) diseases has already been extensively evaluated, and it was found to be an independent predictor of all-cause and cardiovascular mortality ...
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Book Series
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Chapter
Diabetes and Microcirculation
The aim of this chapter is to briefly review available data regarding changes in the structure of microvessels observed in patients with diabetes mellitus and possible correction by effective treatment.
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Heart Failure with Preserved Ejection Fraction: Current Management and Future Strategies Pre-Heart Failure
Chronic heart failure (CHF) is one of the most frequent causes of death and hospitalization. About half of the patients with CHF have a left ventricular ejection fraction (LVEF) > 50%, i.e., a normal or preser...
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Book
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Book
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Article
Open AccessReal-world Antihypertensive Treatment Patterns, Treatment Adherence, and Blood Pressure Control in the Elderly: An Italian Awareness-raising Campaign on Hypertension by Senior Italia FederAnziani, the Italian Society of Hypertension and the Italian Federation of General Practitioners
Achieving hypertension control is beneficial regardless of age. Fixed-combination pills have the potential of increasing adherence to treatment, improving the benefit/risk ratio, and simplifying therapy, with ...
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Article
Open AccessThe UrgeRe (Urgenze Ipertensive: Un Progetto Educazionale Fondato Sulla Vita Reale, Hypertensive Urgencies: A Project in the Real World) Project
The approach to hypertensive emergiencies (HE) and urgencies (HU) may be different according to local clinical practice, despite recent guidelines and position papers recommendations. The Italian Society of Hy...
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Chapter
Prognostic Role of Microvascular Damage and Effect of Treatment
In hypertension, the increase in peripheral resistance occurs at the level of microcirculation. It was clearly demonstrated that wall thickness is increased in relation to internal lumen and that this alterati...
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Chapter
Organ Damage
The impact of arterial hypertension on the structure and function of the heart, the central nervous system, the arterial vessels, and the kidney is responsible for subsequent mortality and morbidity. Evaluatio...
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Chapter
Subclinical Vascular Damage in Prehypertension
The relationship between blood pressure (BP) and cardiovascular events is continuous and therefore the distinction between normotension and hypertension is arbitrary. Despite this, for practical reasons, this ...
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Chapter
Heart Failure with Preserved Ejection Fraction: Current Management and Future Strategies
Hypertension (HTN) represents the most important attributable risk factor for heart failure (HF). The measurement of left ventricular (LV) ejection fraction (EF) is the basis for the description of HF in diffe...
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Chapter
Microvascular Structural Alterations and Tissue Perfusion in Hypertension/Diabetes
The development of structural changes in the systemic vasculature is the end result of established hypertension. Indeed, in essential hypertension, small arteries smooth muscle cell are restructured around a s...
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Article
Use of Antihypertensive Drugs in Neoplastic Patients
The introduction of Vascular Endothelial Growth Factor (VEGF) signaling pathway inhibitor treatment has highlighted the role of the baseline activity of the VEFG system for blood pressure regulation. VEGF sign...
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Article
Open AccessErratum to: Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized “Z” Studies
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Article
Open AccessEfficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized “Z” Studies
Combinations between an angiotensin converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB) and hydrochlorothiazide (HCTZ) are among the recommended treatments for hypertensive patients u...
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Article
Open AccessManagement of Hypercholesterolemia, Appropriateness of Therapeutic Approaches and New Drugs in Patients with High Cardiovascular Risk
Control of lipid levels is one of the most effective strategies for cardiovascular (CV) event prevention. In fact, many clinical trials have clearly demonstrated that low-density lipoprotein cholesterol (LDL-C...
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Chapter
Pathophysiology of Brain Damage in Hypertension: Small Vessel Disease
Structural abnormalities of microvessels are common alterations associated with chronic hypertension. Changes in the microvascular structure of the cerebral circulation, both in terms of an increased media-lum...
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Chapter
The Impact of Uncontrolled Hypertension on the Heart
Available data indicate that raised blood pressure (BP) represents the greatest single contributor to the global burden of disease and to global mortality [1]. According to the results of a large meta-analysis...
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