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    Small heat shock proteins prevent aggregation of citrate synthase and bind to the N-terminal region which is absent in thermostable forms of citrate synthase

    Citrate synthase (CS) is often used in chaperone assays since this thermosensitive enzyme aggregates at moderately increased temperatures. Small heat shock proteins (sHsps) are molecular chaperones specialized...

    Emma Åhrman, Niklas Gustavsson, Claus Hultschig, Wilbert C. Boelens in Extremophiles (2007)