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Article
Open AccessPiplartine eliminates CD34 + AML stem/progenitor cells by inducing oxidative stress and suppressing NF-κB signalling
Acute myeloid leukaemia (AML) is a haematological malignancy characterised by the accumulation of transformed myeloid progenitors in the bone marrow. Piplartine (PL), also known as piperlongumine, is a pro-oxi...
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Article
Open AccessIntegrating stakeholder feedback into the design of a peer-delivered primary care wellness program: A rapid qualitative study
Individuals seen in Primary Care with behavioral health concerns who decline behavioral health treatment may benefit from the support of peers (consumers in recovery from behavioral health concerns employed to...
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Article
The Cost of Cancer: The Association of Financial and Cancer-Related Stress on Maladaptive Co** Styles in Families with a Cancer Diagnosis
According to the American Cancer Society (2020), it is estimated that 1.8 million new cancer diagnoses will occur in 2019 in the United States. Due to the frequency of cancer diagnoses and the increasing costs of...
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Article
Open AccessShock wave formation from head-on collision of two subsonic vortex rings
Vortex ring collisions have attracted intense interest in both water and air studies (Baird in Proc R Soc Lond Ser Math Phys Sci 409:59–65, 1987, Poudel et al. in Phys Fluids 33:096105, 2021, Lim and Nickels i...
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Article
Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity
Stroke is a multiphasic process in which initial cerebral ischemia is followed by secondary injury from immune responses to ischemic brain components. Here we demonstrate that peripheral CD11b+CD45+ myeloid cells...
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Article
Erratum to: Development and refinement of a clinician intervention to facilitate primary care patient use of the PTSD Coach app
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Article
Development and refinement of a clinician intervention to facilitate primary care patient use of the PTSD Coach app
Posttraumatic stress disorder (PTSD) is common and undertreated among Veterans Affairs (VA) primary care patients. A brief primary care intervention combining clinician support with a self-management mobile ap...
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Reference Work Entry In depth
Assessment of Post-Traumatic Stress, Depression, and Anxiety in School-Aged Children
The experience of trauma can have serious and long-term consequences on children’s development and well-being. In this chapter, we review a number of psychometrically valid psychological measures that can be u...
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Living Reference Work Entry In depth
Assessment of Posttraumatic Stress, Depression, and Anxiety in School-Aged Children
The experience of trauma can have serious and long-term consequences on children’s development and well-being. In this chapter, we review a number of psychometrically valid psychological measures that can be u...
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Article
Failure and Delay in Treatment-Seeking Across Anxiety Disorders
Anxiety disorders are a significant mental health problem. Despite the availability of effective treatments most sufferers do not seek help. The current study assesses delays in treatment-seeking, failure to s...