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  1. Article

    Open Access

    Immunologic constant of rejection as a predictive biomarker of immune checkpoint inhibitors efficacy in non-small cell lung cancer

    Anti-PD1/PDL1 immune checkpoint inhibitors (ICI) transformed the prognosis of patients with advanced non-small cell lung cancer (NSCLC). However, the response rate remains disappointing and toxicity may be lif...

    Alice Mogenet, Pascal Finetti, Emilie Denicolai in Journal of Translational Medicine (2023)

  2. Article

    Open Access

    Plasmatic MMP9 released from tumor-infiltrating neutrophils is predictive for bevacizumab efficacy in glioblastoma patients: an AVAglio ancillary study

    We previously identified matrix metalloproteinase 2 (MMP2) and MMP9 plasma levels as candidate biomarkers of bevacizumab activity in patients with recurrent glioblastoma. The aim of this study was to assess th...

    Carine Jiguet-Jiglaire, Sebastien Boissonneau in Acta Neuropathologica Communications (2022)

  3. Article

    Open Access

    Proscillaridin A exerts anti-tumor effects through GSK3β activation and alteration of microtubule dynamics in glioblastoma

    Glioblastoma (GBM) is characterized by highly aggressive growth and invasive behavior. Due to the highly lethal nature of GBM, new therapies are urgently needed and repositioning of existing drugs is a promisi...

    Raphael Berges, Emilie Denicolai, Aurélie Tchoghandjian in Cell Death & Disease (2018)

  4. No Access

    Article

    Changes in PlGF and MET-HGF expressions in paired initial and recurrent glioblastoma

    Angiogenesis is one of the key features of glioblastoma (GB). However, the use of anti-angiogenic therapies directed against vascular endothelial growth factor (VEGF) is limited by primary or acquired resistan...

    Emeline Tabouret, Emilie Denicolai, Christine Delfino in Journal of Neuro-Oncology (2016)