8 Result(s)
within
Elliott Kieff
Biomedicine
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Article
Open AccessEpstein–Barr virus latent genes
Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many human disorders. The persistence of these viral genomes in all malignant cells, yet with the expression of limited latent genes,...
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Chapter
Epstein–Barr Virus Latent Infection Nuclear Proteins: Genome Maintenance and Regulation of Lymphocyte Cell Growth and Survival
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Chapter and Conference Paper
NF-κB Inhibition in EBV-Transformed Lymphoblastoid Cell Lines
Epstein-Barr virus (EBV) transforms B-l/mphocytes into lymphoblastoid cell lines usur** multiple signaling pathways including NF-κB activation. To determine whether NF-κB activity is essential in the growth ...
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Article
Why commonplace encounters turn to fatal attraction
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Article
Molecular basis for Epstein-Barr virus induced pathogenesis and disease
In summary, information obtained from single gene transfer into EBV-negative cell lines is consistent with molecular genetic analysis of in vitro transformation by the whole virus in emphasizing the role for E...
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Chapter
Epstein-Barr Virus Recombinants: Use of Positive Selection Markers to Rescue Mutants in EBV Negative B Lymphoma Cells
Epstein-Barr virus (EBV) genetic analyses have been restricted because the in vitro host range is limited to primate B lymphocytes which are largely non-permissive for EBV replication (1). Further, recovery of...
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Chapter
Epstein-Barr Virus Transformation of B Lymphocytes: Molecular Pathogenesis
Primary Epstein-Barr Virus (EBV) infection begins in the oropharynx where the virus establishes persistent infection of epithelial cells through continued cycles of infection, virus replication, cell death, vi...
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Chapter
Persistence and Expression of the Epstein-Barr Virus Genome in Latent Infection and Growth Transformation of Lymphocytes
Epstein-Barr Virus (EBV) is believed to be an important etiologic agent of nasopharyngeal cancers (NPC) especially of the anaplastic type since (i) NPC cells invariably harbor EBV (Wolf et al., 1975; Huang et ...
