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Article
Systematic review on traumatic intracranial haemorrhage in patients on anti-thrombotic medications; haemorrhage progression, thrombosis, and anti-thrombotic recommencement
A large number of patients who sustain a traumatic intracranial haemorrhage (tICH) are taking anti-thrombotic (AT) medications at the time of injury. These are stopped acutely, but there is uncertainty about s...
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Article
Open AccessHow does research activity align with research need in chronic subdural haematoma: a gap analysis of systematic reviews with end-user selected knowledge gaps
Chronic subdural haematoma (CSDH) is increasingly common. Although treatment is triaged and provided by neurosurgery, the role of non-operative care, alongside observed peri-operative morbidity and patient com...
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Article
Open AccessA systematic review identifying outcome measures used in evaluating adults sustaining cervical spine fractures
To assess the outcome measures used in studies investigating cervical spine fractures in adults, with or without associated spinal cord injury, to inform development of a core outcome set.
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Chapter
Non-functioning Pituitary Adenoma
A 71 year old lady presented to her general practitioner reporting a 1 year history of increasing blurred vision in the right eye and was referred to Ophthalmology. Subsequent assessment revealed reduced visua...
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Article
The changing face of neurosurgery for the older person
Increased life expectancy and illness prevention and treatment have led to a growing population of older patients. These changes in patient population are apparent in neurosurgery; however, relatively little i...
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Article
Open AccessStatistical analysis plan for the Dex-CSDH trial: a randomised, double-blind, placebo-controlled trial of a 2-week course of dexamethasone for adult patients with a symptomatic chronic subdural haematoma
The incidence of chronic subdural haematoma (CSDH) is increasing. Although surgery remains the mainstay of management for symptomatic patients, uncertainty remains regarding the role of steroids. Hence, the De...
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Article
Open AccessDex-CSDH randomised, placebo-controlled trial of dexamethasone for chronic subdural haematoma: report of the internal pilot phase
The Dex-CSDH trial is a randomised, double-blind, placebo-controlled trial of dexamethasone for patients with a symptomatic chronic subdural haematoma. The trial commenced with an internal pilot, whose primary...
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Article
Open AccessCorrection to: Dexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial
After publication of the original article [1], the authors notified that that one of the BNTRC institutional collaborator names was misspelled.
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Article
Open AccessDexamethasone for adult patients with a symptomatic chronic subdural haematoma (Dex-CSDH) trial: study protocol for a randomised controlled trial
Chronic subdural haematoma (CSDH) is a common neurosurgical condition, typically treated with surgical drainage of the haematoma. However, surgery is associated with mortality and morbidity, including up to 20...
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Article
Open AccessThe British Neurosurgical Trainee Research Collaborative: Five years on
Since its inception in 2012, the British Neurosurgical Trainee Research Collaborative (BNTRC) has established itself as a robust example of a trainee-led research collaborative. This article summarises the wor...
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Article
Open AccessPathophysiology of chronic subdural haematoma: inflammation, angiogenesis and implications for pharmacotherapy
Chronic subdural haematoma (CSDH) is an encapsulated collection of blood and fluid on the surface of the brain. Historically considered a result of head trauma, recent evidence suggests there are more complex ...
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Chapter
Chronic Subdural Haematoma in the Elderly
Chronic subdural haematoma (CSDH) is a common condition in the elderly neurosurgical population. It is thought to result from a combination of head trauma followed by an inflammatory reaction in the subdural s...
