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  1. Article

    Open Access

    Mutated Toll-like receptor 9 increases Alzheimer’s disease risk by compromising innate immunity protection

    The development of Alzheimer’s disease (AD) involves central and peripheral immune deregulation. Gene identification and studies of AD genetic variants of peripheral immune components may aid understanding of ...

    Rita Cacace, Lujia Zhou, Elisabeth Hendrickx Van de Craen in Molecular Psychiatry (2023)

  2. Article

    Open Access

    Rare missense mutations in ABCA7 might increase Alzheimer’s disease risk by plasma membrane exclusion

    The adenosine triphosphate–binding cassette subfamily A member 7 gene (ABCA7) is associated with Alzheimer’s disease (AD) in large genome-wide association studies. Targeted sequencing of ABCA7 suggests a role for...

    Liene Bossaerts, Elisabeth Hendrickx Van de Craen in Acta Neuropathologica Communications (2022)