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Article

Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment

Neuroblastoma (NB) is the most common pediatric tumor and is currently treated by several types of therapies including chemotherapies, such as bortezomib treatment. However, resistance to bortezomib is frequen...

Kévin Berthenet, Eliézer Aïmontché, Sara El Mrini, Johan Brière… in Scientific Reports (2024)