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Article
Co** with a newly diagnosed high-grade glioma: patient-caregiver dyad effects on quality of life
Patients with high-grade gliomas (HGG) and their caregivers have to confront a very aggressive disease that produces major lifestyle disruptions. There is an interest in studying the ability of patients and th...
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Article
Open AccessInhibitor of apoptosis protein expression in glioblastomas and their in vitro and in vivo targeting by SMAC mimetic GDC-0152
Glioblastomas (GBMs) are the most aggressive primary brain tumors in adult and remain a therapeutic challenge. Targeting key apoptosis regulators with the ultimate aim to restore apoptosis in tumor cells could...
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Article
Neuro-oncological patients admitted in intensive-care unit: predictive factors and functional outcome
The prognosis of oncology patients admitted to the intensive care unit (ICU) is considered poor. Our objective was to analyze the characteristics and predictive factors of death in the ICU and functional outco...
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Article
Congrès Targeted Anticancer Therapies — TAT 2014
Les actualités majeures des thérapies ciblées antitumorales se sont discutées lors de la dernière édition du congrès TAT (Targeted Anticancer Therapies) à Washington du 5 au 7 mars 2014. Après l’introduction d...
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Article
Limited impact of prognostic factors in patients with recurrent glioblastoma multiforme treated with a bevacizumab-based regimen
Bevacizumab has demonstrated activity in patients with recurrent glioblastoma. However, the impact of prognostic factors associated with recurrent glioblastoma treated with cytotoxic agents has not been determ...