15 Result(s)

Protocol

“Hot Stuff”: The Many Uses of a Radiolabel Assay in Detecting Acyl-Homoserine Lactone Quorum-Sensing Signals

Many Proteobacteria synthesize acyl-homoserine lactone (AHL) molecules for use as signals in cell density-dependent gene regulation known as quorum sensing (QS) and response. AHL detection protocols are essential...

Amy L. Schaefer, Caroline S. Harwood, E. Peter Greenberg in Quorum Sensing (2018)

Article

Progress in and promise of bacterial quorum sensing research

This Review highlights how we can build upon the relatively new and rapidly develo** field of research into bacterial quorum sensing (QS). We now have a depth of knowledge about how bacteria use QS signals t...

Marvin Whiteley, Stephen P. Diggle, E. Peter Greenberg in Nature (2017)

Article

Plan B for quorum sensing

Pseudomonas aeruginosa uses several intertwined cell-cell communication systems, called quorum sensing (QS) systems, to control gene expression. A QS signal–dependent transcription factor called LasR is at the to...

Ajai A Dandekar, E. Peter Greenberg in Nature Chemical Biology (2013)

Chapter

Ironing Out the Biofilm Problem:The Role of Iron in Biofilm Formation

The opportunistic pathogen Pseudomonas aeruginosa causes chronic biofilm-associated infections in the lungs of cystic fibrosis patients that cannot be eradicated by antibiotics. Like most other pathogens, P. aeru...

E. Peter Greenberg, Ehud Banin in Control of Biofilm Infections by Signal Manipulation (2008)

Article

The superficial life of microbes

The social activities and organization of bacteria are crucial to their ecological success. But it is only in recent years that we have begun to study these secret societies.

Roberto Kolter, E. Peter Greenberg in Nature (2006)

Article

Listening in on bacteria: acyl-homoserine lactone signalling

Article

A component of innate immunity prevents bacterial biofilm development

Antimicrobial factors form one arm of the innate immune system, which protects mucosal surfaces from bacterial infection^1,2,3. These factors can rapidly kill bacteria deposited on mucosal surfaces and prevent acu...

Pradeep K. Singh, Matthew R. Parsek, E. Peter Greenberg, Michael J. Welsh in Nature (2002)

Article

Pump up the versatility

Pseudomonas aeruginosais a versatile bacterium that colonizes the lungs of most people with cystic fibrosis. Its genome sequence provides clues to the origins of its versatility and its resistance to antibiotics.

E. Peter Greenberg in Nature (2000)

Article

The intracellular polyglucose storage granules of Spirochaeta aurantia

Extracts of Spirochaeta aurantia contained granules approximately 36 nm in diameter. These granules were purified by isopycnic centrifugation on CsCl gradients and shown on the basis of chemical and spectroscopic...

Andrew M. Kropinski, William C. Ghiorse, E. Peter Greenberg in Archives of Microbiology (1988)

Article

The basis of silver staining of bacterial lipopolysaccharides in polyacrylamide gels

When cast in a polyacrylamide gel, whole lipopolysaccharide (LPS) and the lipid A fraction of LPS fromSalmonella typhimurium andEscherichia coli O111∶B4 reacted with the silver stain described by Tsai and Frasch ...

Dr. Andrew M. Kropinski, Denise Berry, E. Peter Greenberg in Current Microbiology (1986)

Article

Rifampin as a selective agent for the enumeration and isolation of spirochetes from salt marsh habitats

Spirochetes from a variety of salt marsh sediments were enumerated and isolated directly by using a prereduced complex medium containing rifampin as a selective agent. Based on cell morphology, the spirochetal...

Frederick H. Weber, E. Peter Greenberg in Current Microbiology (1981)