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Article
Common variants in the HLA-DRB1–HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis
Jenefer Blackwell, Peter Donnelly and colleagues report a genome-wide association study for visceral leishmaniasis using studies from India and Brazil, with replication in an additional Indian study. They iden...
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Article
Open AccessCXCR1 and SLC11A1polymorphisms affect susceptibility to cutaneous leishmaniasis in Brazil: a case-control and family-based study
L. braziliensis causes cutaneous (CL) and mucosal (ML) leishmaniasis. Wound healing neutrophil (PMN) and macrophage responses made following the bite of the vector sand fly contribute to disease progression in m...
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Article
Are there two classes of VSG gene in Trypanosoma brucei?
Antigenic variation in the African trypanosomes involves the sequential expression of genes coding for different variant surface glycoproteins (VSGs) (reviewed in refs 1–3). When expression of some VSG genes i...