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    The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells

    MS-275 is a histone deacetylase (HDAC) inhibitor that has been reported to mediate its cytotoxic effect through generation of reactive oxygen species (ROS) in proliferating hematopoietic cell lines. We examine...

    D M Lucas, M E Davis, M R Parthun, A P Mone, S Kitada, K D Cunningham, E L Flax… in Leukemia (2004)